Supplement Evidence Check

Check supplement ingredients by research evidence

See what studies suggest, where the evidence is limited, and what cautions are reported.

1Search an ingredient

2Choose a question

3Review evidence and cautions

1Search ingredient

Ingredient

2What are you curious about?

Choose an ingredient to see available effects and caution topics.

Select an ingredient from the list first.

Explore database

Browse by your goal

Explore ingredients studied for sleep, fatigue, stress, and other topics. Tiers classify evidence; they are not purchase rankings.

Compare research consistency and key cautions at a glance.

Tier A

Multiple studies confirm signal

Sodium Bicarbonate

79.3Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Caffeine

78.0Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Tier B

Limited but observed evidence

Tier C

Early or exploratory research

Phosphatidylserine

59.4Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Chondroitin

58.2Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Lecithin

54.8Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Betaine

54.8Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Calcium

51.5Evidence score

Updated This Month10 new papers

Caution:Moderate

Papers:20 studies

Niacin

48.7Evidence score

Updated This Month10 new papers

Caution:Moderate

Papers:20 studies

Alpha-Lipoic Acid

47.2Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Zinc

47.2Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Electrolytes

45.4Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Probiotics

45.1Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Coenzyme Q10

43.9Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Selenium

42.4Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Vitamin A

41.8Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Vitamin E

41.5Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Prebiotics

40.5Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Manganese

37.1Evidence score

Updated This Month10 new papers

Caution:Moderate

Papers:20 studies

Pantothenic Acid

19.9Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Hyaluronic Acid

1.1Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Copper

0.0Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

B Complex

0.0Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

D-Ribose

0.0Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Biotin

0.0Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Vitamin B6

0.0Evidence score

Updated This Month10 new papers

Caution:Low

Papers:20 studies

Check supplement ingredients by research evidence

Browse by your goal

Tier A

Sodium Bicarbonate

Caffeine

Tier B

Beetroot Extract

Beta-Alanine

Potassium

Creatine

HMB

Collagen

Chromium

Citrulline

Taurine

L-Carnitine

L-Theanine

Fiber

Glycine

Melatonin

Vitamin K

Psyllium

Riboflavin

Inulin

Vitamin C

Iodine

Casein Protein

Omega-3

Vitamin B12

Magnesium

Glucosamine

Whey Protein

Berberine

Folate

Vitamin D

Iron

MSM

Inositol

Quercetin

NAC

MCT Oil

Plant Sterols

Thiamine

Tier C

Phosphatidylserine

Chondroitin

Lecithin

Betaine

Calcium

Niacin

Alpha-Lipoic Acid

Zinc

Electrolytes

Probiotics

Coenzyme Q10

Selenium

Vitamin A

Vitamin E

Prebiotics

Manganese

Pantothenic Acid

Hyaluronic Acid

Copper

B Complex

D-Ribose

Biotin

Vitamin B6