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Lemon Balm

Selected research topic

Blood lipids

Findings differ across measurements or study conditions. The results below keep them separate.

Some findings concern patients or people with a deficiency.

Publications for this topic
4
Human comparison publications
2
Publications needing review
1

Findings in the studies

  • LDL

    Publications linked to this measurement: 2

    Human comparison research
    • A better result than the comparison group was reported.

      What the comparison group used was not confirmed.

      Patient group · Single ingredient
      Measurement and study conditions
      Study type
      Randomized controlled trial: subjects were randomly assigned to groups for comparison.
      Study population
      Human participants · Patient group
      Ingredients tested
      Single ingredient
      How results were compared
      Results were compared between groups.
      Measurement time
      Not confirmed.
    Review of existing studies · population needs confirmation
    • The study reported improvement in this measurement.
      Single ingredient
      Measurement and study conditions
      Study type
      Meta-analysis
      Study population
      Recorded population category: Patient group. Whether the research involved humans needs confirmation.
      Ingredients tested
      Single ingredient
      How results were compared
      Results were compared between groups. · Study comparison: Lemon balm versus placebo in pooled trials
      Additional measurement information
      Biomarker
      Measurement time
      Not confirmed.

  • serum level of triglyceride

    Publications linked to this measurement: 1

    • No clear difference from the comparison group was found.
      Patient group · Single ingredient · 2–3 months
      Measurement and study conditions
      Study type
      Randomized controlled trial: subjects were randomly assigned to groups for comparison.
      Study population
      Human participants · Patient group
      Ingredients tested
      Single ingredient
      How results were compared
      Results were compared between groups. · Between-group comparison
      Additional measurement information
      Secondary outcome
      Measurement time
      2–3 months

  • HDL

    Publications linked to this measurement: 1

    Review of existing studies · population needs confirmation
    • No clear difference in this measurement was found between the compared groups.
      Single ingredient
      Measurement and study conditions
      Study type
      Meta-analysis
      Study population
      Recorded population category: Patient group. Whether the research involved humans needs confirmation.
      Ingredients tested
      Single ingredient
      How results were compared
      Results were compared between groups. · Study comparison: Lemon balm versus placebo in pooled trials
      Additional measurement information
      Biomarker
      Measurement time
      Not confirmed.

  • TC

    Publications linked to this measurement: 1

    Review of existing studies · population needs confirmation
    • The study reported improvement in this measurement.
      Single ingredient
      Measurement and study conditions
      Study type
      Meta-analysis
      Study population
      Recorded population category: Patient group. Whether the research involved humans needs confirmation.
      Ingredients tested
      Single ingredient
      How results were compared
      Results were compared between groups. · Study comparison: Lemon balm versus placebo in pooled trials
      Additional measurement information
      Biomarker
      Measurement time
      Not confirmed.
Other measured outcomes (1)

  • TG

    Publications linked to this measurement: 1

    Review of existing studies · population needs confirmation
    • The study reported improvement in this measurement.
      Single ingredient
      Measurement and study conditions
      Study type
      Meta-analysis
      Study population
      Recorded population category: Patient group. Whether the research involved humans needs confirmation.
      Ingredients tested
      Single ingredient
      How results were compared
      Results were compared between groups. · Study comparison: Lemon balm versus placebo in pooled trials
      Additional measurement information
      Biomarker
      Measurement time
      Not confirmed.

This result is held for interpretation. That does not mean research found no effect.

Outcome groups needing additional review (1)
  • total cholesterol · Distinct papers needing additional review: 1Evidence criteria check: 1

One paper can appear under multiple measured outcomes or review reasons, so these counts should not be added together.

Representative outcome and study details

Human studies reported between-group improvement in LDL; while Studies with an unspecified organism reported between-group improvement in LDL.

These conditions come from related studies and may not describe a single paper.

Single-ingredient studies · Human studies · Includes patient groups · between-group comparison

2 publications linked to this result

  • Study conditions differ; results are shown descriptively and are not pooled.
Data coverage and detailed study classifications

Paper counts are separated by research topic below. One paper may contribute to multiple findings.

Analysis status: Public-ready

Ingredient analysis date:

How the grade was determined: C

The 33.5 evidence score includes 1 independent human studies and 1 clinical studies in the representative benefit area. The C tier remains conservative because of limited repetition across independent human clinical studies, too few clinical findings with an explicit effect direction.

The grade is based mainly on the research area with the most evidence. It does not mean the same result was found in other areas.

Papers linked to this ingredient overall: 58

Papers linked to this topic 4 · distinct papers 4 · papers with a confirmed human comparison 2 · papers needing additional review 1

A publication may appear in more than one count. These numbers should not be added. Ingredient-wide papers, topic-linked papers, and sources in outcome groups use different scopes. Adding source counts may count the same paper more than once.

  • HDL: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • LDL: Sources represented in this measurement group: 2 · Distinct papers with human comparisons for this outcome: 1
  • serum level of triglyceride: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 1
  • TC: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • TG: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • total cholesterol: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0

What the research found

serum level of triglyceride

No clear difference in this measurement was found between the compared groups.

Controlled study in people · Single ingredient · Patient group

Between-group comparison

Analysis coverage and paper counts

1 paper · 1 measured outcome

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

LDL

The study reported improvement in this measurement.

Controlled study in people · Single ingredient · Patient group

Between-group comparison

Analysis coverage and paper counts

1 paper · 1 measured outcome

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

HDL

No clear difference in this measurement was found between the compared groups.

Meta-analysis · Single ingredient · Patient group

Between-group comparison

Analysis coverage and paper counts

1 paper · 1 measured outcome

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

LDL

The study reported improvement in this measurement.

Meta-analysis · Single ingredient · Patient group

Between-group comparison

Analysis coverage and paper counts

1 paper · 1 measured outcome

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

TC

The study reported improvement in this measurement.

Meta-analysis · Single ingredient · Patient group

Between-group comparison

Analysis coverage and paper counts

1 paper · 1 measured outcome

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

TG

The study reported improvement in this measurement.

Meta-analysis · Single ingredient · Patient group

Between-group comparison

Analysis coverage and paper counts

1 paper · 1 measured outcome

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

total cholesterol

The study needs further checking before its result can be interpreted.

Meta-analysis · Single ingredient · Unspecified population

The comparison could not be confirmed.

Analysis coverage and paper counts

1 paper · 1 measured outcome

1 papers held from direction counts

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

How to read research findings

How should I read research findings?

Research guides

Side effects and combination findings

Findings from this ingredient alone are shown separately from those involving another supplement or medication.

No reviewed caution rules are available yet. Reported caution findings are shown below.

Findings to review with care

Side effects reported for the ingredient alone are separated from findings involving another supplement or medication.

Side effects reported with this ingredient alone

Symptoms or adverse events reported in studies without another active ingredient.

LD501 papers
Acute oral toxicity of lemon balm essential oil in BALB/c mice showed significant behavioral, biochemical, and pathological changes at doses >1 g kg‑1, with an LD50 of 2.57 g kg‑1.Animal studies · Animal study