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Thiamine

Selected research topic

Blood lipids

Confirmed comparison evidence for this topic is limited. The findings below retain their study conditions.

Findings from a combination study cannot be attributed to this ingredient alone.

Some publications still need interpretation checks and are kept separate from the findings below.

Some findings concern patients or people with a deficiency.

Publications for this topic
2
Human comparison publications
0
Publications needing review
1

Findings in the studies

  • total cholesterol

    Publications linked to this measurement: 1

    Other human research, including observational studies and reviews
    • A change was reported before and after use. Its cause cannot be isolated.
      Patient group · Single ingredient · 3 months for total cholesterol
      Measurement and study conditions
      Study type
      Clinical trial
      Study population
      Human participants · Patient group
      Ingredients tested
      Single ingredient
      How results were compared
      Changes within the same group were compared. · Study comparison: Follow-up after thiamine; no between-group treatment contrast reported
      Additional measurement information
      Secondary outcome
      Measurement time
      3 months for total cholesterol

  • high-density lipoprotein (HDL)

    Publications linked to this measurement: 1

    Review of existing studies · population needs confirmation
    • A result was reported, but the comparison could not be confirmed.

      Several ingredients were tested together, so this ingredient’s individual effect is unknown.

      Combination study · 3-month follow-up
      Measurement and study conditions
      Study type
      Systematic review
      Study population
      Recorded population category: Patient group. Whether the research involved humans needs confirmation.
      Ingredients tested
      Ingredient combination
      How results were compared
      Study comparison: included thiamine/benfotiamine studies; comparator not stated in this summary
      Additional measurement information
      Biomarker
      Measurement time
      3-month follow-up
Representative outcome and study details

Studies with an unspecified organism reported a result with no confirmed comparison group in high-density lipoprotein (HDL).

combination-ingredient studies · Individual ingredient effects cannot be separated · Includes patient groups · comparator not confirmed

1 publications linked to this result

  • Route, form, dose, or population details are incomplete, so the findings cannot be confirmed as directly comparable.
  • Combination, formula, or class studies do not isolate this ingredient or establish synergy.
Data coverage and detailed study classifications

Paper counts are separated by research topic below. One paper may contribute to multiple findings.

Analysis status: Public-ready

Ingredient analysis date:

How the grade was determined: C

The 16.9 evidence score includes 0 independent human studies and 0 clinical studies in the representative benefit area. The C tier remains conservative because of limited repetition across independent human clinical studies, too few clinical findings with an explicit effect direction.

The grade is based mainly on the research area with the most evidence. It does not mean the same result was found in other areas.

Papers linked to this ingredient overall: 82

Papers linked to this topic 2 · distinct papers 2 · comparison findings need further review · papers needing additional review 1

A publication may appear in more than one count. These numbers should not be added. Ingredient-wide papers, topic-linked papers, and sources in outcome groups use different scopes. Adding source counts may count the same paper more than once.

  • high-density lipoprotein (HDL): Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • total cholesterol: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0

What the research found

total cholesterol

A change was reported before and after use. Its cause cannot be isolated.

Other evidence · Single ingredient · Patient group

Within-group comparison

Analysis coverage and paper counts

1 paper · 1 measured outcome

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

high-density lipoprotein (HDL)

A result was reported, but the comparison could not be confirmed.

Review · Ingredient combination · Patient group

Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

Analysis coverage and paper counts

1 paper · 1 measured outcome

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

Unspecified measured outcome

The study needs further checking before its result can be interpreted.

Meta-analysis · Unknown intervention · Patient group

The comparison could not be confirmed.

Analysis coverage and paper counts

1 paper · 1 measured outcome

1 papers held from direction counts

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

How to read research findings

How should I read research findings?

Research guides

Side effects and combination findings

Findings from this ingredient alone are shown separately from those involving another supplement or medication.

No combination cautions are available to show in the current data. This does not guarantee safety.

Side effects and combination studies

No side-effect or combination findings are available to show from the collected papers. This does not establish safety.