Key Evidence #1
reviewPublic scholarly dataCitation signal: 147
Existing evidence is suggestive of a beneficial effect of Mg on subjective anxiety in anxiety vulnerable samples, however, the quality of the existing evidence is poor.
Tier-BPublic-ready6/11/2026
Magnesium
Glucose and metabolic health markers is closer to a research marker, so it should be read separately from a directly felt benefit.
Representative tier calculated from paper evidence that passed the collection audit.
Papers analyzed
20
Caution signal
Low
Representative score
65.2
Glucose and metabolic health markersStress Response and Sleep ChangesNutrient status markers
Main benefit evidence
The representative ingredient tier is calculated from these target-level evidence groups.
Glucose and metabolic health4 studiesTier-BGlucose and metabolic health markersFairly consistent positive signal in studiesResearch marker focusPatient-group studyThis card is closer to a measured biomarker or lab outcome than a directly felt user benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Glucose and metabolic health
4 studiesTier-B
Glucose and metabolic health markers
Fairly consistent positive signal in studiesResearch marker focusPatient-group study
This card is closer to a measured biomarker or lab outcome than a directly felt user benefit.
Closer to a research marker than a directly felt benefit.
Open metrics
>Glucose and metabolic markers
No direct rate reported. Read direction and evidence strength together.
Evidence score
54.6
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Stress and mood3 studiesTier-BStress Response and Sleep ChangesFairly consistent positive signal in studiesFelt benefit focusPatient-group studyThese findings come from stress response, cortisol, anxiety, or sleep outcomes. They may mix felt benefits with physiological markers.Open metrics>
Stress and mood
3 studiesTier-B
Stress Response and Sleep Changes
Fairly consistent positive signal in studiesFelt benefit focusPatient-group study
These findings come from stress response, cortisol, anxiety, or sleep outcomes. They may mix felt benefits with physiological markers.
Open metrics
>Stress and mood balanceSleep quality
No direct rate reported. Read direction and evidence strength together.
Evidence score
52.0
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Nutrient status2 studiesTier-CNutrient status markersFairly consistent positive signal in studiesResearch marker focusPatient-group studyThis card is closer to a measured biomarker or lab outcome than a directly felt user benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Nutrient status
2 studiesTier-C
Nutrient status markers
Fairly consistent positive signal in studiesResearch marker focusPatient-group study
This card is closer to a measured biomarker or lab outcome than a directly felt user benefit.
Closer to a research marker than a directly felt benefit.
Open metrics
>Nutrient status and deficiency markers
No direct rate reported. Read direction and evidence strength together.
Evidence score
48.7
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Condition-specific evidence1 studiesTier-CCondition-specific health context in a specific contextSome positive signal observedResearch marker focusSupplement contextThis result was studied for Condition-specific health context in a narrower population or condition-specific context. It should not be generalized as an everyday supplement effect.Closer to a research marker than a directly felt benefit.Open metrics>
Condition-specific evidence
1 studiesTier-C
Condition-specific health context in a specific context
Some positive signal observedResearch marker focusSupplement context
This result was studied for Condition-specific health context in a narrower population or condition-specific context. It should not be generalized as an everyday supplement effect.
Closer to a research marker than a directly felt benefit.
Open metrics
>Condition-specific health context
No direct rate reported. Read direction and evidence strength together.
Evidence score
43.7
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Blood lipids1 studiesTier-CCholesterol and triglyceridesSome positive signal observedFelt benefit focusPatient-group studyPotential benefit studied in Blood lipids.Open metrics>
Blood lipids
1 studiesTier-C
Cholesterol and triglycerides
Some positive signal observedFelt benefit focusPatient-group study
Potential benefit studied in Blood lipids.
Open metrics
>Cholesterol and triglycerides
No direct rate reported. Read direction and evidence strength together.
Evidence score
43.5
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Recent research
Updated This Month10 new papers
10 new papers were added in this period. No new risk signal was identified.
What's new
10 new papers were added.No new risk signal was identified.
Most notable recent finding
This is the most meaningful new study in the latest update.
Why it mattersIt ranked highest among the newly collected papers for this ingredient in the latest update.
View paperKey cautions to review
Standalone side-effect signals and combination cautions are listed separately.
Caution index
1.4
Caution band: Low
Caution signals
0
Side effects + combos + curated rules
Key precautions
No combination caution signal is clear enough to show right now. This does not guarantee safety.
Standalone side effects, combination cautions, and positive combos are separated below.
Side-effect and combination signals
No standalone side-effect or combination signal is currently clear enough to show from the collected papers. This does not mean there is no concern.
Evidence summaries
Paper IDs and full lists are private. Only study types and summaries are shown.
Key Evidence #2
observationalPublic scholarly dataCitation signal: 144
Data suggest that VitK2 supplementation might improve bone quality and reduce fracture risk in osteoporotic patients, potentially enhancing the efficacy of Ca ± vitD and Mg supplementation, but data regarding the effectiveness of vitK2 and MG supplementation o
Key Evidence #3
observationalPublic scholarly dataCitation signal: 129
MgO, but not AST-120, appears to be effective in slowing CAC progression in CKD, and larger-scale trials are warranted to confirm these findings.
3 more summariesLimited representative sample by study type.>
Public scholarly dataCitation signal: 117
observational[Abstract]: Current treatment options for depression are limited by efficacy, cost, availability, side effects, and acceptability to patients. Several studies have looked at the association between magnesium and depression, yet its role in symptom management i
Public scholarly dataCitation signal: 79
observationalOverall, magnesium supplementation for 12 weeks among subjects with DFU had beneficial effects on parameters of ulcer size, glucose metabolism, serum hs-CRP, and plasma TAC levels.
Public scholarly dataCitation signal: 76
observationalThe results of this study revealed that oral Mg supplementation reduces insulin resistance and improves the glycemic control indicators among T2D patients.
Magnesium
arrow_backBack to listEvidence score: 65.2|Caution index: 1.4