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Thiamine

Selected research topic

Glucose and metabolic health

Confirmed comparison evidence for this topic is limited. The findings below retain their study conditions.

Findings from a combination study cannot be attributed to this ingredient alone.

Publications for this topic
6
Human comparison publications
1
Publications needing review
3

Findings in the studies

  • risk of GDM

    Publications linked to this measurement: 1

    Other human research, including observational studies and reviews
    • An association was observed. This does not establish that the ingredient caused the change.
      Single ingredient · first and second trimesters
      Measurement and study conditions
      Study type
      Observational study
      Study population
      Human participants · Participant characteristics were not confirmed.
      Ingredients tested
      Single ingredient
      How results were compared
      Results were compared between groups. · Study comparison: higher versus lowest quartile of total thiamine intake; cohort association
      Measurement time
      first and second trimesters

  • diabetes

    Publications linked to this measurement: 1

    Review of existing studies · population needs confirmation
    • A result was reported, but the comparison could not be confirmed.
      Single ingredient
      Measurement and study conditions
      Study type
      Review
      Study population
      Recorded population category: Deficiency group. Whether the research involved humans needs confirmation.
      Ingredients tested
      Single ingredient
      How results were compared
      Study comparison: Review-level report of thiamine supplementation in genetic deficiency; no comparator specified
      Measurement time
      Not confirmed.

  • FBG

    Publications linked to this measurement: 1

    Review of existing studies · population needs confirmation
    • A result was reported, but the comparison could not be confirmed.

      Several ingredients were tested together, so this ingredient’s individual effect is unknown.

      Combination study · up to 3 months
      Measurement and study conditions
      Study type
      Systematic review
      Study population
      Recorded population category: Patient group. Whether the research involved humans needs confirmation.
      Ingredients tested
      Ingredient combination
      How results were compared
      Study comparison: thiamine/benfotiamine trial synthesis; comparison not stated in this summary
      Additional measurement information
      Biomarker
      Measurement time
      up to 3 months

  • HbA1c

    Publications linked to this measurement: 1

    Review of existing studies · population needs confirmation
    • A result was reported, but the comparison could not be confirmed.

      Several ingredients were tested together, so this ingredient’s individual effect is unknown.

      Combination study · up to 3 months
      Measurement and study conditions
      Study type
      Systematic review
      Study population
      Recorded population category: Patient group. Whether the research involved humans needs confirmation.
      Ingredients tested
      Ingredient combination
      How results were compared
      Study comparison: thiamine/benfotiamine trial synthesis; comparison not stated in this summary
      Additional measurement information
      Biomarker
      Measurement time
      up to 3 months
Other measured outcomes (1)

  • PPG

    Publications linked to this measurement: 1

    Review of existing studies · population needs confirmation
    • A result was reported, but the comparison could not be confirmed.

      Several ingredients were tested together, so this ingredient’s individual effect is unknown.

      Combination study · up to 3 months
      Measurement and study conditions
      Study type
      Systematic review
      Study population
      Recorded population category: Patient group. Whether the research involved humans needs confirmation.
      Ingredients tested
      Ingredient combination
      How results were compared
      Study comparison: thiamine/benfotiamine trial synthesis; comparison not stated in this summary
      Additional measurement information
      Biomarker
      Measurement time
      up to 3 months

This result is held for interpretation. That does not mean research found no effect.

Outcome groups needing additional review (1)
  • Glucose · Distinct papers needing additional review: 1Direction unclear: 1

One paper can appear under multiple measured outcomes or review reasons, so these counts should not be added together.

Representative outcome and study details

Studies with an unspecified organism reported a result with no confirmed comparison group in diabetes.

Single-ingredient studies · Includes deficiency groups · comparator not confirmed

1 publications linked to this result

  • Route, form, dose, or population details are incomplete, so the findings cannot be confirmed as directly comparable.
Data coverage and detailed study classifications

Paper counts are separated by research topic below. One paper may contribute to multiple findings.

Analysis status: Public-ready

Ingredient analysis date:

How the grade was determined: C

The 16.9 evidence score includes 0 independent human studies and 0 clinical studies in the representative benefit area. The C tier remains conservative because of limited repetition across independent human clinical studies, too few clinical findings with an explicit effect direction.

The grade is based mainly on the research area with the most evidence. It does not mean the same result was found in other areas.

Papers linked to this ingredient overall: 82

Papers linked to this topic 6 · distinct papers 6 · papers with a confirmed human comparison 1 · papers needing additional review 3

A publication may appear in more than one count. These numbers should not be added. Ingredient-wide papers, topic-linked papers, and sources in outcome groups use different scopes. Adding source counts may count the same paper more than once.

  • diabetes: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • FBG: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • Glucose: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • HbA1c: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • PPG: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • risk of GDM: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 1

What the research found

risk of GDM

An association was observed. This does not establish that the ingredient caused the change.

Observational study · Single ingredient · Unspecified population

Between-group comparison

Analysis coverage and paper counts

1 paper · 1 measured outcome

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

diabetes

A result was reported, but the comparison could not be confirmed.

Review · Single ingredient · Deficiency group

Analysis coverage and paper counts

1 paper · 1 measured outcome

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

FBG

A result was reported, but the comparison could not be confirmed.

Review · Ingredient combination · Patient group

Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

Analysis coverage and paper counts

1 paper · 1 measured outcome

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

HbA1c

A result was reported, but the comparison could not be confirmed.

Review · Ingredient combination · Patient group

Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

Analysis coverage and paper counts

1 paper · 1 measured outcome

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

PPG

A result was reported, but the comparison could not be confirmed.

Review · Ingredient combination · Patient group

Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

Analysis coverage and paper counts

1 paper · 1 measured outcome

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

Glucose

The study needs further checking before its result can be interpreted.

Controlled study in people · Ingredient combination · Patient group

Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

Between-group comparison

Analysis coverage and paper counts

1 paper · 1 measured outcome

1 papers held from direction counts

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

Unspecified measured outcome

The study needs further checking before its result can be interpreted.

Animal study · indirect · Single ingredient · Patient group

This finding comes from animal or cell research. It does not establish the same effect in people.

The comparison could not be confirmed.

Analysis coverage and paper counts

1 paper · 1 measured outcome

1 papers held from direction counts

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

Unspecified measured outcome

The study needs further checking before its result can be interpreted.

Other evidence · Single ingredient · Patient group

The comparison could not be confirmed.

Analysis coverage and paper counts

1 paper · 1 measured outcome

1 papers held from direction counts

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

How to read research findings

How should I read research findings?

Research guides

Side effects and combination findings

Findings from this ingredient alone are shown separately from those involving another supplement or medication.

No combination cautions are available to show in the current data. This does not guarantee safety.

Side effects and combination studies

No side-effect or combination findings are available to show from the collected papers. This does not establish safety.