biotech

Bio-Analyst

Research Platform
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Tier-CPublic-ready7/3/2026

Vitamin E

Cholesterol and triglycerides is the main area connected here, and any felt benefit should be read together with the human evidence base.

The 33.7 score includes research signals from patient or disease contexts. General supplement evidence is not repeated enough, so the C tier remains conservative.

Representative tier calculated from paper evidence that passed the collection audit.

Papers analyzed
116
Caution signal
Low
Context-specific research signal
33.7
Cholesterol and triglyceridesMale Reproductive Health MarkersBlood pressure and vascular health markers

Main benefit evidence

The representative ingredient tier is calculated from these target-level evidence groups.

Blood lipids
4 studiesTier-C
Cholesterol and triglycerides
Some positive signal observedFelt benefit focusPatient-group study

Potential benefit studied in Blood lipids. These findings come from a defined study population, so everyday effects may differ.

Evidence score
44.6
Study context
Patient-group study

This score reflects the strength of this benefit group. The ingredient tier also considers paper count, repetition, population, and study context.

Men's health
3 studiesTier-C
Male Reproductive Health Markers
Some positive signal observedResearch marker focusPatient-group study

These findings come from sperm, semen, or hormone markers such as testosterone, LH, FSH, and inhibin B. They are closer to research measurements than a directly felt benefit. These findings come from a defined study population, so everyday effects may differ.

Evidence score
29.2
Study context
Patient-group study

This score reflects the strength of this benefit group. The ingredient tier also considers paper count, repetition, population, and study context.

Blood pressure and vascular health
1 studiesTier-C
Blood pressure and vascular health markers
Signal is still limitedResearch marker focusPatient-group study

This card is closer to a measured biomarker or lab outcome than a directly felt user benefit. These findings come from a defined study population, so everyday effects may differ.

Evidence score
6.8
Study context
Patient-group study

This score reflects the strength of this benefit group. The ingredient tier also considers paper count, repetition, population, and study context.

Recent research

Updated This Month10 new papers

Observed range in repeated studies

This range includes studies in specific patient groups. It is not a general dose or recommendation.

Lower observed study value
5
mg/day
Higher observed study value
900
mg/day
Only ranges repeated in human, oral, single-ingredient studies are shown.
Not personal dosing instructions, recommendations, or safety limits.

Side effects and combination findings in studies

Findings from studies of this ingredient alone are separated from findings involving another supplement or medication.

Caution index
0.8
Caution band: Low
Caution signals
4
Side effects + combos + curated rules
Key precautions
No curated contraindication rule is available yet, but literature caution signals are shown below.
2 combo signals and 0 added-signal combos shown below.
These are signals reported in studies. They do not predict what will happen to an individual.

Findings to review with care

Side effects reported for the ingredient alone are separated from findings involving another supplement or medication.

Side effects reported when this ingredient was used alone

Symptoms or adverse events reported in studies of this ingredient without another active ingredient.

Adverse effect signal1 papers
High-dose vitamin E consumption was reported in three patients with cryptogenic intracerebral hemorrhage and acutely elevated serum alpha-tocopherol levels, suggesting an association between hypervitaminosis E and increased bleeding risk.Human studies · Study type not identified
Adverse effect signal1 papers
A statistically nonsignificant increased risk of prostate cancer was reported with vitamin E alone (RR = 1.13, P = 0.06).Human studies · Study type not identified

Caution signals when used with another supplement or medication

These studies reported a negative change, reduced absorption, or another caution when substances were used together. They do not predict an individual outcome.

와파린Vitamin E's anticoagulant effects amplify the risk of bleeding when combined with blood thinners like warfarin.
AspirinVitamin E's anticoagulant effects amplify the risk of bleeding when combined with blood thinners like aspirin.

Positive combinations studied

Positive combination findings are separated by how the study compared the groups. This is not a recommendation to combine them.

Positive findings when used together

The combination had a positive result, but the contribution of each ingredient could not be separated.

비타민 CIn a triple-blind RCT of 60 women with endometriosis, a combination of Vitamin C (1000 mg/day) and Vitamin E (800 IU/day) for 8 weeks significantly reduced pelvic pain, dysmenorrhea, and dyspareunia compared to placebo.
인삼The combined supplement significantly improved the desire domain of the FSFI compared to placebo.

Evidence summaries

Paper IDs and full lists are private. Only study types and summaries are shown.

Key Evidence #1
Public scholarly dataCitation signal: 651
review

An expanding body of evidence support that members of the vitamin E family are functionally unique, and title claims in manuscripts should be limited to the specific form of vitamin E studied.

Key Evidence #2
Public scholarly dataCitation signal: 276
review

While both tocopherols exhibit anti-inflammatory activity in vitro and in vivo, supplementation with mixed (gammaT-enriched) tocopHerols seems to be more potent than supplementation with alphaT alone, which may explain the mostly negative outcomes of the recen

Key Evidence #3
Public scholarly dataCitation signal: 270
meta-analysis

[Abstract]: We studied the effect of vitamin C, vitamin E, and beta carotene intake on the risk of Parkinson's disease (PD). We did a systematic review and meta-analysis of observational studies published between 1966 and March 2005 searching MEDLINE, EMBASE,

3 more summariesLimited representative sample by study type.
>
Public scholarly dataCitation signal: 221
rct

[Abstract]: Increased dietary vitamin E intake is associated with a reduced incidence of asthma, and combinations of antioxidant supplements including vitamin E are effective in reducing ozone induced bronchoconstriction. A study was undertaken to investigate

Public scholarly dataCitation signal: 196
review

From a health point of view, at the moment there is a great interest in the natural forms of tocochromanols, because they are considered promising compounds able to maintain a healthy cardiovascular system and satisfactory blood cholesterol levels.

Public scholarly dataCitation signal: 187
rct

[Abstract]: Oxidative stress may play a key role in the development of cognitive impairment. Long-term supplementation with vitamin E, a strong antioxidant, may provide cognitive benefits. The Women's Health Study is a randomized, double-blind, placebo-control

Vitamin E
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