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Bio-Analyst

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Tier-CPublic-ready6/11/2026

Vitamin E

Menstrual and women's health is the main area connected here, and any felt benefit should be read together with the human evidence base.

Representative tier calculated from paper evidence that passed the collection audit.

Papers analyzed
20
Caution signal
Low
Representative score
41.5
Menstrual and women's healthNutrient status markersCondition-specific health context in a specific context

Main benefit evidence

The representative ingredient tier is calculated from these target-level evidence groups.

Women's health
1 studiesTier-C
Menstrual and women's health
Some positive signal observedFelt benefit focusPatient-group study
Potential benefit studied in Women's health.
Open metrics
>
Menstrual and women's health
No direct rate reported. Read direction and evidence strength together.
Evidence score
44.0
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Nutrient status
1 studiesTier-C
Nutrient status markers
Some positive signal observedResearch marker focusPatient-group study
This card is closer to a measured biomarker or lab outcome than a directly felt user benefit.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Nutrient status and deficiency markers
No direct rate reported. Read direction and evidence strength together.
Evidence score
44.0
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Condition-specific evidence
1 studiesTier-C
Condition-specific health context in a specific context
Some positive signal observedResearch marker focusSupplement context
This result was studied for Condition-specific health context in a narrower population or condition-specific context. It should not be generalized as an everyday supplement effect.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Condition-specific health context
No direct rate reported. Read direction and evidence strength together.
Evidence score
41.7
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Skin, hair, and nails
1 studiesTier-C
Skin, hair, and nail support
Signal is still limitedFelt benefit focusPatient-group study
Potential benefit studied in Skin, hair, and nails.
Open metrics
>
Skin, hair, and nail support
No direct rate reported. Read direction and evidence strength together.
Evidence score
12.9
Score reflects signal strength. Tier also considers paper count, repetition, and study context.

Recent research

Updated This Month10 new papers

10 new papers were added in this period. No new risk signal was identified.

What's new

10 new papers were added.No new risk signal was identified.

Most notable recent finding

This is the most meaningful new study in the latest update.
review
Why it mattersIt ranked highest among the newly collected papers for this ingredient in the latest update.
View paper

Study dosage range (reference only)

Lower dose
15
mg/day
Higher dose
15
mg/day
Dosages used in research papers, shown as reference context.
Not personal dosing instructions, recommendations, or safety limits.

Key cautions to review

Standalone side-effect signals and combination cautions are listed separately.

Caution index
0.4
Caution band: Low
Caution signals
0
Side effects + combos + curated rules
Key precautions
No combination caution signal is clear enough to show right now. This does not guarantee safety.
2 combo signals and 0 added-signal combos shown below.
Standalone side effects, combination cautions, and positive combos are separated below.

Combinations studied together

The group showed a positive signal, but individual contributions are hard to isolate. Not a stack recommendation.

+Omega-3Combined supplementation with omega-3 fatty acids, carotenoids, and 15 mg/day vitamin E for 24 months significantly reduced working memory errors in cognitively healthy older adults compared to placebo.
+SeleniumCombined supplementation with Selenium and Vitamin E demonstrated significant improvement in ovarian reserve markers compared to placebo.

Evidence summaries

Paper IDs and full lists are private. Only study types and summaries are shown.

Key Evidence #1
Public scholarly dataCitation signal: 69
review

A review of the literature about the role of vitamin E supplementation on diabetic nephropathy is performed, also describing the underlying antioxidant, anti-inflammatory, and metabolic mechanisms to evaluate the possible use of tocopherols and tocotrienols in

Key Evidence #2
Public scholarly dataCitation signal: 137
observational

The intake of vitamin C and vitamin E supplements effectively reduced dysmenorrhea severity and improved dyspareunia and severity of pelvic pain, and support the potential role of antioxidants in the management of endometriosis.

Key Evidence #3
Public scholarly dataCitation signal: 92
observational

The results support a biologically plausible rationale whereby these nutrients work synergistically, and in a dose-dependent manner, to improve working memory in cognitively healthy older adults.

3 more summariesLimited representative sample by study type.
>
Public scholarly dataCitation signal: 78
meta-analysis

There is currently insufficient evidence to support a potential beneficial effect of vitamin E supplementation on improvements of HbA1c and fasting glucose and insulin concentrations in subjects with T2DM.

Public scholarly dataCitation signal: 67
observational

The purpose of the present meta‐analysis is to investigate the effects of vitamin E supplementation in biochemical and histological parameters in adult patients with NAFLD.

Public scholarly dataCitation signal: 66
observational

Vitamin E supplementation to hyperthyroid animals limits the thyroid hormone-induced increases in mitochondrial ROS and oxidative damage, and prevents the reduction of the high functionality components of the mitochondrial population induced byhyperthyroidism,

Vitamin E
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