biotech
Bio-AnalystSupplement research
person

Saffron

Selected research topic

Glucose and metabolic health

Some measured outcomes improved in human comparison studies. Read these findings with their populations and conditions.

Some findings concern patients or people with a deficiency.

Publications for this topic
7
Human comparison publications
2
Publications needing review
4

Findings in the studies

  • Fasting Blood Sugar

    • A better result than the comparison group was reported.

      What the comparison group used was not confirmed.

      Patient group · Single ingredient
      Measurement and study conditions
      Study type
      Randomized controlled trial: subjects were randomly assigned to groups for comparison.
      Study population
      Human participants · Patient group
      Ingredients tested
      Single ingredient
      How results were compared
      Results were compared between groups.
      Measurement time
      Not confirmed.
  • Fasting plasma glucose

    Human comparison research
    • A better result than the comparison group was reported.

      What the comparison group used was not confirmed.

      Patient group · Single ingredient
      Measurement and study conditions
      Study type
      Randomized controlled trial: subjects were randomly assigned to groups for comparison.
      Study population
      Human participants · Patient group
      Ingredients tested
      Single ingredient
      How results were compared
      Results were compared between groups.
      Measurement time
      Not confirmed.
    Research with unclear study subject or type
    • A change was reported, but the comparison could not be confirmed.
      varied across included trials
      Measurement and study conditions
      Study type
      Meta-analysis
      Study population
      Recorded population category: General population. Whether the research involved humans needs confirmation.
      Ingredients tested
      Unknown intervention
      How results were compared
      Study comparison: High-quality-study subgroup pooled outcome; comparator details not reported
      Additional measurement information
      Secondary outcome
      Measurement time
      varied across included trials
  • body weight

    Research with unclear study subject or type
    • A change was reported, but the comparison could not be confirmed.
      varied across included trials
      Measurement and study conditions
      Study type
      Meta-analysis
      Study population
      Recorded population category: General population. Whether the research involved humans needs confirmation.
      Ingredients tested
      Unknown intervention
      How results were compared
      Study comparison: Pooled outcome across included trials; comparator details not reported
      Additional measurement information
      Secondary outcome
      Measurement time
      varied across included trials
  • fasting insulin

    Research with unclear study subject or type
    • A change was reported, but the comparison could not be confirmed.
      varied across included trials
      Measurement and study conditions
      Study type
      Meta-analysis
      Study population
      Recorded population category: General population. Whether the research involved humans needs confirmation.
      Ingredients tested
      Unknown intervention
      How results were compared
      Study comparison: Pooled outcome across included trials; comparator details not reported
      Additional measurement information
      Secondary outcome
      Measurement time
      varied across included trials
Other measured outcomes (1)
  • waist circumstance

    Research with unclear study subject or type
    • A change was reported, but the comparison could not be confirmed.
      varied across included trials
      Measurement and study conditions
      Study type
      Meta-analysis
      Study population
      Recorded population category: General population. Whether the research involved humans needs confirmation.
      Ingredients tested
      Unknown intervention
      How results were compared
      Study comparison: Pooled outcome across included trials; comparator details not reported
      Additional measurement information
      Secondary outcome
      Measurement time
      varied across included trials

This result is held for interpretation. That does not mean research found no effect.

Outcome groups needing additional review (4)
  • antihyperglycemic properties · Distinct papers needing additional review: 1Evidence criteria check: 1
  • FBS · Distinct papers needing additional review: 1Evidence criteria check: 1
  • FPG · Distinct papers needing additional review: 1Evidence criteria check: 1
  • hypoglycemic potentials · Distinct papers needing additional review: 1Direction unclear: 1

One paper can appear under multiple measured outcomes or review reasons, so these counts should not be added together.

Representative outcome and study details

Human studies reported between-group improvement in Fasting plasma glucose; while Studies with an unspecified organism reported a change with no confirmed comparison group in Fasting plasma glucose.

These conditions come from related studies and may not describe a single paper.

Single-ingredient studies · Scope not specified · Human studies · Includes patient groups · between-group comparison · comparator not confirmed

2 publications linked to this result

  • Study conditions differ; results are shown descriptively and are not pooled.
Data coverage and detailed study classifications

Paper counts are separated by research topic below. One paper may contribute to multiple findings.

Analysis status: Public-ready

Ingredient analysis date:

How the grade was determined: C

The 39.7 evidence score includes 1 independent human studies and 1 clinical studies in the representative benefit area. The C tier remains conservative because of limited repetition across independent human clinical studies, too few clinical findings with an explicit effect direction.

The grade is based mainly on the research area with the most evidence. It does not mean the same result was found in other areas.

Papers linked to this ingredient overall: 97

Papers linked to this topic 7 · distinct papers 7 · papers with a confirmed human comparison 2 · papers needing additional review 4

A publication may appear in more than one count. These numbers should not be added. Ingredient-wide papers, topic-linked papers, and sources in outcome groups use different scopes. Adding source counts may count the same paper more than once.

  • antihyperglycemic properties: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • body weight: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • Fasting Blood Sugar: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 1
  • fasting insulin: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • Fasting plasma glucose: Sources represented in this measurement group: 2 · Distinct papers with human comparisons for this outcome: 1
  • FBS: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • FPG: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • hypoglycemic potentials: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
  • waist circumstance: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0

What the research found

Fasting Blood Sugar

The study reported improvement in this measurement.

Controlled study in people · Single ingredient · Patient group

Between-group comparison

Analysis coverage and paper counts

1 paper · 1 measured outcome

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

Fasting plasma glucose

The study reported improvement in this measurement.

Controlled study in people · Single ingredient · Patient group

Between-group comparison

Analysis coverage and paper counts

1 paper · 1 measured outcome

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

body weight

A change was reported, but the comparison could not be confirmed.

Meta-analysis · Unknown intervention · General population

Analysis coverage and paper counts

1 paper · 1 measured outcome

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

fasting insulin

A change was reported, but the comparison could not be confirmed.

Meta-analysis · Unknown intervention · General population

Analysis coverage and paper counts

1 paper · 1 measured outcome

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

fasting plasma glucose

A change was reported, but the comparison could not be confirmed.

Meta-analysis · Unknown intervention · General population

Analysis coverage and paper counts

1 paper · 1 measured outcome

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

waist circumstance

A change was reported, but the comparison could not be confirmed.

Meta-analysis · Unknown intervention · General population

Analysis coverage and paper counts

1 paper · 1 measured outcome

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

antihyperglycemic properties

The study needs further checking before its result can be interpreted.

Review · Unknown intervention · Patient group

The comparison could not be confirmed.

Analysis coverage and paper counts

1 paper · 1 measured outcome

1 papers held from direction counts

Review overlap with primary papers is unknown; counts stay separate.

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

FBS

The study needs further checking before its result can be interpreted.

Controlled study in people · Single ingredient · Patient group

Between-group comparison

Analysis coverage and paper counts

1 paper · 1 measured outcome

1 papers held from direction counts

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

FPG

The study needs further checking before its result can be interpreted.

Controlled study in people · Single ingredient · Patient group

Between-group comparison

Analysis coverage and paper counts

1 paper · 1 measured outcome

1 papers held from direction counts

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

hypoglycemic potentials

The study needs further checking before its result can be interpreted.

Other evidence · Unknown intervention · Patient group

Between-group comparison

Analysis coverage and paper counts

1 paper · 1 measured outcome

1 papers held from direction counts

Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

How to read research findings

How should I read research findings?

Research guides

Side effects and combination findings

Findings from this ingredient alone are shown separately from those involving another supplement or medication.

No combination cautions are available to show in the current data. This does not guarantee safety.

Side effects and combination studies

No side-effect or combination findings are available to show from the collected papers. This does not establish safety.