Improvement after a supplement is not the same as a comparative result
Start with the comparison. A before-and-after change alone cannot isolate the contribution of an ingredient.
Ginseng
Selected research topic
Fatigue and energy
Human comparison studies did not find a clear difference in some measured outcomes.
Some findings concern patients or people with a deficiency.
- Publications for this topic
- 5
- Human comparison publications
- 1
- Publications needing review
- 3
Findings in the studies
total NRS score
Publications linked to this measurement: 1
- No clear difference from the comparison group was found.Patient group · Single ingredient · 4 weeks
Measurement and study conditions
- Study type
- Randomized controlled trial: subjects were randomly assigned to groups for comparison.
- Study population
- Human participants · Patient group
- Ingredients tested
- Single ingredient
- How results were compared
- Results were compared between groups. · Study comparison: 1 g or 2 g Panax ginseng extract versus placebo
- Additional measurement information
- Primary outcome
- Measurement time
- 4 weeks
disease-related fatigue
Publications linked to this measurement: 1
Review of existing studies · population needs confirmation
- A result was reported, but the comparison could not be confirmed.varied
Measurement and study conditions
- Study type
- Meta-analysis
- Study population
- Recorded population category: Patient group. Whether the research involved humans needs confirmation.
- Ingredients tested
- Unknown intervention
- How results were compared
- Study comparison: Meta-analysis of ginseng supplement trials; comparator details not supplied in abstract
- Additional measurement information
- Primary outcome
- Measurement time
- varied
fatigue reduction
Publications linked to this measurement: 1
Review of existing studies · population needs confirmation
- The study reported improvement in this measurement.Single ingredient
Measurement and study conditions
- Study type
- Meta-analysis
- Study population
- Study subject not identified
- Ingredients tested
- Single ingredient
- How results were compared
- Results were compared between groups. · Study comparison: ginseng supplements versus placebo across separate RCT sets
- Measurement time
- unspecified across included trials
This result is held for interpretation. That does not mean research found no effect.
Outcome groups needing additional review (2)
- general fatigue · Distinct papers needing additional review: 1Evidence criteria check: 1
- subjective feelings of mental fatigue · Distinct papers needing additional review: 1Evidence criteria check: 1
One paper can appear under multiple measured outcomes or review reasons, so these counts should not be added together.
Representative outcome and study details
Studies with an unspecified organism reported a result with no confirmed comparison group in disease-related fatigue.
Scope not specified · Includes patient groups · comparator not confirmed
1 publications linked to this result
- Route, form, dose, or population details are incomplete, so the findings cannot be confirmed as directly comparable.
Data coverage and detailed study classifications
Paper counts are separated by research topic below. One paper may contribute to multiple findings.
Analysis status: Public-ready
Ingredient analysis date:
How the grade was determined: C
The 37.7 evidence score includes 2 independent human studies and 2 clinical studies in the representative benefit area. The C tier remains conservative because of limited repetition across independent human clinical studies, limited repeated evidence for directly felt outcomes.
The grade is based mainly on the research area with the most evidence. It does not mean the same result was found in other areas.
Papers linked to this ingredient overall: 91
Papers linked to this topic 5 · distinct papers 5 · papers with a confirmed human comparison 1 · papers needing additional review 3
A publication may appear in more than one count. These numbers should not be added. Ingredient-wide papers, topic-linked papers, and sources in outcome groups use different scopes. Adding source counts may count the same paper more than once.
- disease-related fatigue: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
- fatigue reduction: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
- general fatigue: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
- subjective feelings of mental fatigue: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 0
- total NRS score: Sources represented in this measurement group: 1 · Distinct papers with human comparisons for this outcome: 1
What the research found
total NRS score
No clear difference in this measurement was found between the compared groups.
Controlled study in people · Single ingredient · Patient group
Between-group comparison
Analysis coverage and paper counts
1 paper · 1 measured outcome
Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.
fatigue reduction
The study reported improvement in this measurement.
Meta-analysis · Single ingredient · Unspecified population
Between-group comparison
Analysis coverage and paper counts
1 paper · 1 measured outcome
Review overlap with primary papers is unknown; counts stay separate.
Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.
disease-related fatigue
A result was reported, but the comparison could not be confirmed.
Meta-analysis · Unknown intervention · Patient group
Analysis coverage and paper counts
1 paper · 1 measured outcome
Review overlap with primary papers is unknown; counts stay separate.
Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.
general fatigue
The study needs further checking before its result can be interpreted.
Other evidence · Ingredient combination · General population
Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.
Within-group comparison
Analysis coverage and paper counts
1 paper · 1 measured outcome
1 papers held from direction counts
Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.
subjective feelings of mental fatigue
The study needs further checking before its result can be interpreted.
Controlled study in people · Single ingredient · General population
Within-group comparison
Analysis coverage and paper counts
1 paper · 1 measured outcome
1 papers held from direction counts
Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.
Unspecified measured outcome
The study needs further checking before its result can be interpreted.
Controlled study in people · Single ingredient · Patient group
Between-group comparison
Analysis coverage and paper counts
1 paper · 2 measured outcomes
1 papers held from direction counts
Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.
How to read research findings
How should I read research findings?
Research guidesNo clear difference and an uninterpretable result are different
A reported null comparison contains a result. An abstract without an interpretable comparison leaves a question unresolved.
Paper counts and study counts are different
Count original research separately from research that reanalyzes it. Publication volume is neither replication nor a quality rating.
Side effects and combination findings
Findings from this ingredient alone are shown separately from those involving another supplement or medication.
No combination cautions are available to show in the current data. This does not guarantee safety.
Review 1 combination findings and 0 findings that outperformed an ingredient alone.
Reported improvements with combinations
Combination findings are grouped by how the study compared them. This is not a recommendation to combine ingredients.
Combinations with reported improvement
The combination showed improvement, but each ingredient's contribution is unclear.
비타민 EThe combined supplement significantly improved the desire domain of the FSFI compared to placebo.