biotech
Bio-AnalystSupplement research
person
arrow_backExplore/Ashwagandha

Ashwagandha

Women's health

Some findings are held for review

Some papers have not cleared source or result review, so their findings are not summarized yet.

No confirmed result is available to summarize with study conditions.

A distinct publication count is not available.

Other outcomes and study details

Distinct publications linked to this topic: 1

  • Those papers are not summarized until review is complete.

The current data are insufficient to judge results for this topic.

Research topics to explore

Research topics to explore

Review findings reported in each research area.

Topics with more linked papers appear first.

  • Stress and mood

    Related papers 22 · human comparison papers 2

    View results
    • anxiety-depression cluster scores · Improvement reported · Some studies included patients or people with a deficiency
    • depression single-item · Improvement reported · Some studies included patients or people with a deficiency

    More outcome groups: 14

  • Men's health

    Related papers 14 · human comparison papers 4

    View results
    • Semen volume · Improvement reported
    • Sperm concentration · Improvement reported

    More outcome groups: 13

  • Sleep

    Related papers 12 · human comparison papers 1

    View results
    • final sleep · Improvement reported
    • Groningen Sleep Quality Scale · Interpretation held

    More outcome groups: 8

  • Cognition

    Related papers 8 · human comparison papers 2

    View results
    • logical memory I · Improvement reported · Some studies included patients or people with a deficiency
    • Working Memory · Improvement reported

    More outcome groups: 5

  • Immune and respiratory health

    Related papers 7 · comparison findings need further review

    View results
    • immune homeostasis · Interpretation held
    • mean time for clinical recovery · Interpretation held

    More outcome groups: 1

  • Glucose and metabolic health

    Related papers 6 · human comparison papers 1

    View results
    • Body weight · Improvement reported
    • blood glucose · Some studies included patients or people with a deficiency · Comparison details unconfirmed

    More outcome groups: 1

  • Exercise performance

    Related papers 5 · comparison findings need further review

    View results
    • aerobic endurance · Finding details are limited
    • endurance · Interpretation held

    More outcome groups: 4

  • Fatigue and energy

    Related papers 2 · comparison findings need further review

    View results
    • Chalder Fatigue Scale · Interpretation held
    • fatigue · Interpretation held
  • Nutrient status

    Related papers 2 · comparison findings need further review

    View results
  • Blood lipids

    Related papers 1 · comparison findings need further review

    View results
    • lipid profiles · Finding details are limited
  • Digestion and gut health

    Related papers 1 · human comparison papers 1

    View results
    • Patient Assessment of Constipation-Symptoms (PAC-SYM) · Improvement reported · Some studies used more than one ingredient
  • Women's health

    Related papers 1 · comparison findings need further review

    View selected result
Data coverage and detailed study classifications

Paper counts are separated by research topic below. One paper may contribute to multiple findings.

Analysis status: Public-ready

Ingredient analysis date:

How the grade was determined: B

The 55.9 evidence score includes 6 independent human studies and 6 clinical studies in the representative benefit area. The B tier remains conservative because of limited repetition across independent human clinical studies.

The grade is based mainly on the research area with the most evidence. It does not mean the same result was found in other areas.

Papers linked to this ingredient overall: 126

Papers linked to this topic 1 · distinct papers 1 · comparison findings need further review · papers needing additional review 1

Ingredient-wide papers, topic-linked papers, and sources in outcome groups use different scopes. Adding source counts may count the same paper more than once.

    Stress and mood

    What the research found

    anxiety-depression cluster scores

    The study reported improvement in this measurement.

    Controlled study in people · Single ingredient · Patient group

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    depression single-item

    The study reported improvement in this measurement.

    Controlled study in people · Single ingredient · Patient group

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    HAMA scores

    The study reported improvement in this measurement.

    Controlled study in people · Ingredient combination · Patient group

    Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    anti-anxiety activity

    A change was reported, but the comparison could not be confirmed.

    Review · Unknown intervention · Patient group

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    anxiety

    A change was reported, but the comparison could not be confirmed.

    Meta-analysis · Single ingredient · Unspecified population

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    depression

    A change was reported, but the comparison could not be confirmed.

    Meta-analysis · Single ingredient · Unspecified population

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Serum cortisol

    A change was reported, but the comparison could not be confirmed.

    Controlled study in people · Single ingredient · Unspecified population

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    stress

    A change was reported, but the comparison could not be confirmed.

    Meta-analysis · Single ingredient · Unspecified population

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    anxiety

    The study needs further checking before its result can be interpreted.

    Animal study · indirect · Ingredient combination · Patient group

    This finding comes from animal or cell research. It does not establish the same effect in people.

    Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    anxiety

    The study needs further checking before its result can be interpreted.

    Review · Unknown intervention · General population

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    anxiety reduction

    The study needs further checking before its result can be interpreted.

    Review · Unknown intervention · General population

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    cortisol

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Patient group

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    cortisol levels

    The study needs further checking before its result can be interpreted.

    Review · Unknown intervention · General population

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    depression-like behavior

    The study needs further checking before its result can be interpreted.

    Animal study · indirect · Ingredient combination · Patient group

    This finding comes from animal or cell research. It does not establish the same effect in people.

    Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    generalized anxiety disorder

    The study needs further checking before its result can be interpreted.

    Review · Single ingredient · Patient group

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    HAM-A

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · General population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Perceived Stress Scale

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · General population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Perceived Stress Scale (PSS)

    The study needs further checking before its result can be interpreted.

    Meta-analysis · Unknown intervention · Patient group

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    serum cortisol

    The study needs further checking before its result can be interpreted.

    Animal study · indirect · Single ingredient · General population

    This finding comes from animal or cell research. It does not establish the same effect in people.

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    serum cortisol

    The study needs further checking before its result can be interpreted.

    Observational study · Single ingredient · General population

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Ingredient combination · Unspecified population

    Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 2 measured outcomes

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Review · Ingredient combination · Patient group

    Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 2 measured outcomes

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Animal study · indirect · Single ingredient · Patient group

    This finding comes from animal or cell research. It does not establish the same effect in people.

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Unspecified population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Unspecified population

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Other evidence · Single ingredient · Patient group

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Review · Unknown intervention · Unspecified population

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Men's health

    What the research found

    Sperm count

    Results for this measurement were mixed; no consistent conclusion can be drawn.

    Controlled study in people · Single ingredient · Patient group

    Between-group comparison

    Analysis coverage and paper counts

    2 papers · 2 measured outcomes

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Semen volume

    The study reported improvement in this measurement.

    Controlled study in people · Single ingredient · Unspecified population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Sperm concentration

    The study reported improvement in this measurement.

    Controlled study in people · Single ingredient · Unspecified population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Sperm morphology

    The study reported improvement in this measurement.

    Controlled study in people · Single ingredient · Unspecified population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Testosterone

    The study reported improvement in this measurement.

    Controlled study in people · Single ingredient · Unspecified population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    luteinizing hormone

    A change was reported, but the comparison could not be confirmed.

    Meta-analysis · Single ingredient · Patient group

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    semen volume

    A change was reported, but the comparison could not be confirmed.

    Meta-analysis · Single ingredient · Patient group

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    sperm concentration

    A change was reported, but the comparison could not be confirmed.

    Meta-analysis · Single ingredient · Patient group

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    sperm count

    A change was reported, but the comparison could not be confirmed.

    Controlled study in people · Single ingredient · Patient group

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    sperm count and motility

    A change was reported, but the comparison could not be confirmed.

    Review · Unknown intervention · Patient group

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    sperm motility

    A change was reported, but the comparison could not be confirmed.

    Meta-analysis · Single ingredient · Patient group

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    sperm parameters

    A change was reported, but the comparison could not be confirmed.

    Review · Unknown intervention · Patient group

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    T levels

    A change was reported, but the comparison could not be confirmed.

    Review · Unknown intervention · General population

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    testosterone

    A change was reported, but the comparison could not be confirmed.

    Meta-analysis · Single ingredient · Patient group

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    testosterone levels

    A change was reported, but the comparison could not be confirmed.

    Review · Unknown intervention · Patient group

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    mount and intromission frequency

    The study needs further checking before its result can be interpreted.

    Animal study · indirect · Ingredient combination · Patient group

    This finding comes from animal or cell research. It does not establish the same effect in people.

    Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    semen parameters

    The study needs further checking before its result can be interpreted.

    Review · Unknown intervention · Patient group

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    serum testosterone levels

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Patient group

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    testosterone

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Patient group

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    testosterone levels

    The study needs further checking before its result can be interpreted.

    Review · Unknown intervention · Patient group

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    testosterone levels in men

    The study needs further checking before its result can be interpreted.

    Review · Unknown intervention · General population

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Unspecified population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Sleep

    What the research found

    final sleep

    The study reported improvement in this measurement.

    Controlled study in people · Single ingredient · General population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Groningen Sleep Quality Scale

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Ingredient combination · Unspecified population

    Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    non-rapid eye movement sleep

    The study needs further checking before its result can be interpreted.

    Animal study · indirect · Single ingredient · Patient group

    This finding comes from animal or cell research. It does not establish the same effect in people.

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    overall sleep

    The study needs further checking before its result can be interpreted.

    Meta-analysis · Unknown intervention · General population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    perceived sleep quality

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · General population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    sleep disturbances

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Patient group

    Within-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    sleep duration

    The study needs further checking before its result can be interpreted.

    Animal study · indirect · Single ingredient · Patient group

    This finding comes from animal or cell research. It does not establish the same effect in people.

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    sleep duration

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Patient group

    Within-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    sleep onset latency

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Patient group

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    sleep onset latency

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Patient group

    Within-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Sleep quality

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Unspecified population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    sleep quality

    The study needs further checking before its result can be interpreted.

    Review · Unknown intervention · General population

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    subjective sleep quality

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Patient group

    Within-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Review · Unknown intervention · Patient group

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Cognition

    What the research found

    logical memory I

    The study reported improvement in this measurement.

    Controlled study in people · Single ingredient · Patient group

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Working Memory

    The study reported improvement in this measurement.

    Other evidence · Single ingredient · Unspecified population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    cognitive benefits

    A change was reported, but the comparison could not be confirmed.

    Review · Single ingredient · Patient group

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    cognition

    The study needs further checking before its result can be interpreted.

    Review · Single ingredient · Unspecified population

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    hippocampal-dependent spatial memory

    The study needs further checking before its result can be interpreted.

    Animal study · indirect · Single ingredient · Unspecified population

    This finding comes from animal or cell research. It does not establish the same effect in people.

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    immediate memory

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Ingredient combination · Patient group

    Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    memory performance

    The study needs further checking before its result can be interpreted.

    Animal study · indirect · Ingredient combination · Patient group

    This finding comes from animal or cell research. It does not establish the same effect in people.

    Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Review · Single ingredient · Patient group

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Immune and respiratory health

    What the research found

    immune homeostasis

    The study needs further checking before its result can be interpreted.

    Review · Unknown intervention · Patient group

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    mean time for clinical recovery

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Ingredient combination · Patient group

    Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    SARS-CoV-2 infection

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · General population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Patient group

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Other evidence · Single ingredient · Patient group

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Review · Unknown intervention · Patient group

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Review · Unknown intervention · Unspecified population

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Glucose and metabolic health

    What the research found

    Body weight

    The study reported improvement in this measurement.

    Controlled study in people · Single ingredient · Unspecified population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    blood glucose

    An association was observed. This does not establish that the ingredient caused the change.

    Observational study · Single ingredient · Patient group

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    HbA1c

    The study needs further checking before its result can be interpreted.

    Review · Ingredient combination · Patient group

    Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Animal study · indirect · Single ingredient · Unspecified population

    This finding comes from animal or cell research. It does not establish the same effect in people.

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    2 papers · 2 measured outcomes

    2 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Review · Single ingredient · Unspecified population

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Exercise performance

    What the research found

    aerobic endurance

    The study reported improvement in this measurement.

    Meta-analysis · Single ingredient · General population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    endurance

    The study needs further checking before its result can be interpreted.

    Review · Unknown intervention · General population

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    muscular strength

    The study needs further checking before its result can be interpreted.

    Review · Unknown intervention · General population

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    physical performance

    The study needs further checking before its result can be interpreted.

    Meta-analysis · Single ingredient · General population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Review overlap with primary papers is unknown; counts stay separate.

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    strength in muscle activity

    The study needs further checking before its result can be interpreted.

    Other evidence · Single ingredient · General population

    Within-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    TQR

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · General population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Fatigue and energy

    What the research found

    Chalder Fatigue Scale

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Unspecified population

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    fatigue

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Patient group

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Nutrient status

    What the research found

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Other evidence · Ingredient combination · Patient group

    Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Animal study · indirect · Single ingredient · Unspecified population

    This finding comes from animal or cell research. It does not establish the same effect in people.

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Other evidence · Single ingredient · Patient group

    The comparison could not be confirmed.

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Blood lipids

    What the research found

    lipid profiles

    A change was reported before and after use. Its cause cannot be isolated.

    Controlled study in people · Single ingredient · General population

    Within-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Digestion and gut health

    What the research found

    Patient Assessment of Constipation-Symptoms (PAC-SYM)

    The study reported improvement in this measurement.

    Controlled study in people · Ingredient combination · Unspecified population

    Several ingredients were used together. This does not establish the effect of this ingredient alone or synergy.

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    Women's health

    What the research found

    Unspecified measured outcome

    The study needs further checking before its result can be interpreted.

    Controlled study in people · Single ingredient · Patient group

    Between-group comparison

    Analysis coverage and paper counts

    1 paper · 1 measured outcome

    1 papers held from direction counts

    Direction counts are distinct papers within each row. Outcome contributions count endpoint results, so one paper may contribute more than once.

    How to read research findings

    How should I read research findings?

    Research guides

    Side effects and combination findings

    Findings from this ingredient alone are shown separately from those involving another supplement or medication.

    Caution findings
    2
    Findings from individual and combined use, plus reviewed cautions
    Key precautions
    No reviewed caution rules are available yet. Reported caution findings are shown below.
    These findings were reported in studies. They do not predict an individual's experience.

    Findings to review with care

    Side effects reported for the ingredient alone are separated from findings involving another supplement or medication.

    Side effects reported with this ingredient alone

    Symptoms or adverse events reported in studies without another active ingredient.

    hepatotoxicity1 papers
    The review indicates that Ashwagandha has inherent hepatotoxicity potential based on narrative review of liver toxicity of traditional Indian herbs.Human studies · Systematic review
    adverse effects1 papers
    Ashwagandha has been associated with side effects and potential drug-herb interactions, though specific details are not quantified in this review.Human studies · Systematic review