biotech

Bio-Analyst

Research Platform
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Tier-CPublic-ready6/11/2026

Selenium

Nutrient status markers is closer to a research marker, so it should be read separately from a directly felt benefit.

Representative tier calculated from paper evidence that passed the collection audit.

Papers analyzed
20
Caution signal
Low
Representative score
42.4
Nutrient status markersGlucose and metabolic health markersCholesterol and triglycerides

Main benefit evidence

The representative ingredient tier is calculated from these target-level evidence groups.

Nutrient status
2 studiesTier-C
Nutrient status markers
Fairly consistent positive signal in studiesResearch marker focusPatient-group study
This card is closer to a measured biomarker or lab outcome than a directly felt user benefit.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Nutrient status and deficiency markers
No direct rate reported. Read direction and evidence strength together.
Evidence score
48.7
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Glucose and metabolic health
1 studiesTier-C
Glucose and metabolic health markers
Some positive signal observedResearch marker focusPatient-group study
This card is closer to a measured biomarker or lab outcome than a directly felt user benefit.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Glucose and metabolic markers
No direct rate reported. Read direction and evidence strength together.
Evidence score
44.0
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Blood lipids
1 studiesTier-C
Cholesterol and triglycerides
Some positive signal observedFelt benefit focusPatient-group study
Potential benefit studied in Blood lipids.
Open metrics
>
Cholesterol and triglycerides
No direct rate reported. Read direction and evidence strength together.
Evidence score
44.0
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Women's health
1 studiesTier-C
Menstrual and women's health
Some positive signal observedFelt benefit focusPatient-group study
Potential benefit studied in Women's health.
Open metrics
>
Menstrual and women's health
No direct rate reported. Read direction and evidence strength together.
Evidence score
44.0
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Stress and mood
1 studiesTier-C
Stress Response and Sleep Changes
Some positive signal observedFelt benefit focusPatient-group study
These findings come from stress response, cortisol, anxiety, or sleep outcomes. They may mix felt benefits with physiological markers.
Open metrics
>
Stress and mood balance
No direct rate reported. Read direction and evidence strength together.
Evidence score
42.1
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Condition-specific evidence
2 studiesTier-C
Condition-specific health context in a specific context
Some positive signal observedResearch marker focusSupplement context
This result was studied for Condition-specific health context in a narrower population or condition-specific context. It should not be generalized as an everyday supplement effect.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Condition-specific health context
No direct rate reported. Read direction and evidence strength together.
Evidence score
30.2
Score reflects signal strength. Tier also considers paper count, repetition, and study context.

Recent research

Updated This Month10 new papers

10 new papers were added in this period. No new risk signal was identified.

What's new

10 new papers were added.No new risk signal was identified.

Most notable recent finding

This is the most meaningful new study in the latest update.
review
Why it mattersIt ranked highest among the newly collected papers for this ingredient in the latest update.
View paper

Key cautions to review

Standalone side-effect signals and combination cautions are listed separately.

Caution index
0.8
Caution band: Low
Caution signals
0
Side effects + combos + curated rules
Key precautions
No combination caution signal is clear enough to show right now. This does not guarantee safety.
1 combo signals and 0 added-signal combos shown below.
Standalone side effects, combination cautions, and positive combos are separated below.

Combinations studied together

The group showed a positive signal, but individual contributions are hard to isolate. Not a stack recommendation.

+ProbioticCo-supplementation with probiotics and selenium resulted in significant improvements in mental health, hormonal, and inflammatory parameters compared to placebo.

Evidence summaries

Paper IDs and full lists are private. Only study types and summaries are shown.

Key Evidence #1
Public scholarly dataCitation signal: 329
observational

Selenium supplementation, compared with the placebo, significantly reduced serum high sensitivity C-reactive protein (hs-CRP), insulin, and homeostasis model of assessment-insulin resistance (HOMA-IR) and total-/HDL-cholesterol ratio, and significantly increas

Key Evidence #2
Public scholarly dataCitation signal: 248
review

The antioxidant role of nutritional supplementation of selenium in the management of major chronic metabolic disorders, including hyperlipidaemia, hyperglycaemia, and hyperphenylalaninemia is reviewed.

Key Evidence #3
Public scholarly dataCitation signal: 188
observational

Based on the study results, nano-Se especially synthesized by the biological method at diet levels of 25 or 50 mg/kg improved the growth performance, kidney and liver functions, carcass traits, antioxidants indices, and inflammatory cytokines of growing rabbit

3 more summariesLimited representative sample by study type.
>
Public scholarly dataCitation signal: 132
observational

Overall, the co-administration of probiotic and selenium for 12 weeks to women with PCOS had beneficial effects on mental health parameters, serum total testosterone, hirsutism, hs-CRP, TAC, GSH and MDA levels.

Public scholarly dataCitation signal: 123
observational

Sel-Plex, being a highly bioavailable supplement of organic Se, might represent a suitable option for supplementation of fish feeds, to achieve the final aim of improving fish fitness and resistance against immune challenges.

Public scholarly dataCitation signal: 97
observational

Significantly reduced cardiovascular mortality could be seen in those on selenium and coenzyme Q10 intervention and the protective action was not confined to the intervention period, but persisted during the follow-up period.

Selenium
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