Selenium supplementation, compared with the placebo, significantly reduced serum high sensitivity C-reactive protein (hs-CRP), insulin, and homeostasis model of assessment-insulin resistance (HOMA-IR) and total-/HDL-cholesterol ratio, and significantly increas
Selenium
Nutrient status markers is closer to a research marker, so it should be read separately from a directly felt benefit.
Representative tier calculated from paper evidence that passed the collection audit.
Main benefit evidence
The representative ingredient tier is calculated from these target-level evidence groups.
Nutrient status2 studiesTier-CNutrient status markersFairly consistent positive signal in studiesResearch marker focusPatient-group studyThis card is closer to a measured biomarker or lab outcome than a directly felt user benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Glucose and metabolic health1 studiesTier-CGlucose and metabolic health markersSome positive signal observedResearch marker focusPatient-group studyThis card is closer to a measured biomarker or lab outcome than a directly felt user benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Blood lipids1 studiesTier-CCholesterol and triglyceridesSome positive signal observedFelt benefit focusPatient-group studyPotential benefit studied in Blood lipids.Open metrics>
Women's health1 studiesTier-CMenstrual and women's healthSome positive signal observedFelt benefit focusPatient-group studyPotential benefit studied in Women's health.Open metrics>
Stress and mood1 studiesTier-CStress Response and Sleep ChangesSome positive signal observedFelt benefit focusPatient-group studyThese findings come from stress response, cortisol, anxiety, or sleep outcomes. They may mix felt benefits with physiological markers.Open metrics>
Condition-specific evidence2 studiesTier-CCondition-specific health context in a specific contextSome positive signal observedResearch marker focusSupplement contextThis result was studied for Condition-specific health context in a narrower population or condition-specific context. It should not be generalized as an everyday supplement effect.Closer to a research marker than a directly felt benefit.Open metrics>
Recent research
10 new papers were added in this period. No new risk signal was identified.
What's new
Most notable recent finding
Key cautions to review
Standalone side-effect signals and combination cautions are listed separately.
Combinations studied together
The group showed a positive signal, but individual contributions are hard to isolate. Not a stack recommendation.
Evidence summaries
Paper IDs and full lists are private. Only study types and summaries are shown.
The antioxidant role of nutritional supplementation of selenium in the management of major chronic metabolic disorders, including hyperlipidaemia, hyperglycaemia, and hyperphenylalaninemia is reviewed.
Based on the study results, nano-Se especially synthesized by the biological method at diet levels of 25 or 50 mg/kg improved the growth performance, kidney and liver functions, carcass traits, antioxidants indices, and inflammatory cytokines of growing rabbit
3 more summariesLimited representative sample by study type.>
Overall, the co-administration of probiotic and selenium for 12 weeks to women with PCOS had beneficial effects on mental health parameters, serum total testosterone, hirsutism, hs-CRP, TAC, GSH and MDA levels.
Sel-Plex, being a highly bioavailable supplement of organic Se, might represent a suitable option for supplementation of fish feeds, to achieve the final aim of improving fish fitness and resistance against immune challenges.
Significantly reduced cardiovascular mortality could be seen in those on selenium and coenzyme Q10 intervention and the protective action was not confined to the intervention period, but persisted during the follow-up period.