biotech

Bio-Analyst

Research Platform
person
Tier-CPublic-ready6/12/2026

Manganese

Glucose and metabolic health markers is closer to a research marker, so it should be read separately from a directly felt benefit.

Representative tier calculated from paper evidence that passed the collection audit.

Papers analyzed
20
Caution signal
Moderate
Representative score
37.1
Glucose and metabolic health markersBone, joint, and mobilityExercise performance and recovery

Main benefit evidence

The representative ingredient tier is calculated from these target-level evidence groups.

Glucose and metabolic health
1 studiesTier-C
Glucose and metabolic health markers
Some positive signal observedResearch marker focusPatient-group study
This card is closer to a measured biomarker or lab outcome than a directly felt user benefit.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Glucose and metabolic markers
No direct rate reported. Read direction and evidence strength together.
Evidence score
44.0
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Bone and joint health
1 studiesTier-C
Bone, joint, and mobility
Some positive signal observedFelt benefit focusSupplement context
Potential benefit studied in Bone and joint health.
Open metrics
>
Bone, joint, and mobility
No direct rate reported. Read direction and evidence strength together.
Evidence score
40.5
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Exercise performance and recovery
1 studiesTier-C
Exercise performance and recovery
Some positive signal observedFelt benefit focusPatient-group study
Potential benefit studied in Exercise performance and recovery.
Open metrics
>
Exercise performance and recovery
No direct rate reported. Read direction and evidence strength together.
Evidence score
22.8
Score reflects signal strength. Tier also considers paper count, repetition, and study context.

Recent research

Updated This Month10 new papers

10 new papers were added in this period. No new risk signal was identified.

What's new

10 new papers were added.No new risk signal was identified.

Most notable recent finding

This is the most meaningful new study in the latest update.
meta-analysis
Why it mattersIt ranked highest among the newly collected papers for this ingredient in the latest update.
View paper

Key cautions to review

Standalone side-effect signals and combination cautions are listed separately.

Caution index
2.5
Caution band: Moderate
Caution signals
1
Side effects + combos + curated rules
Key precautions
No combination caution signal is clear enough to show right now. This does not guarantee safety.
Standalone side effects, combination cautions, and positive combos are separated below.

Standalone side effects

Half-maximal Inhibitory Concentration (IC50)1 papers
Mn exhibited toxic effects and VFA accumulation at concentrations >1000 mg/L, with an IC50 of 773.9 mg/L.in-vitro · in-vitro

Evidence summaries

Paper IDs and full lists are private. Only study types and summaries are shown.

Key Evidence #1
Public scholarly dataCitation signal: 1571
review

To control the pandemic of developmental neurotoxicity, a global prevention strategy is proposed and chemicals in existing use and all new chemicals must therefore be tested for developmental neurotoxicity is proposed.

Key Evidence #2
Public scholarly dataCitation signal: 86
review

The aim of this paper was to review recent literature and summarize the newest findings on fluctuations in the concentration of some essential macro- and microelements in those patients with a history of chronic alcohol abuse, mainly on four elements: Iron, ma

Key Evidence #3
Public scholarly dataCitation signal: 71
observational

The results showed the methane yield increased by 59.3%, 47.1% and 48.9% in the first 10 days following addition of Mo, Se and Mn, which has changed the bacterial structure of the bacteria, which in turn has affected the digestion performance.

3 more summariesLimited representative sample by study type.
>
Public scholarly dataCitation signal: 69
review

The adverse effects of manganese exposure from drinking water on school-aged children is sufficiently demonstrated and further investigation into the subject to address inconsistencies in existing studies is recommended.

Public scholarly dataCitation signal: 67
review

A systematic review of studies examining children’s exposure to Mn and neurodevelopmental outcomes focused on selection of biomarker-based and environmental measurements of Mn exposure to identify the scientific advances and research gaps found hair biomarkers

Public scholarly dataCitation signal: 65
review

Hair is the most reliable indicator of manganese exposure for children at 6–18 years of age, although the preliminary meta-analysis found that higher W-Mn was associated with better Performance IQ only in boys, at a relatively low waterManganese concentrations

Manganese
arrow_backBack to list