This study confirmed that BBR and Prob (B. breve) could exert a synergistic hypolipidemic effect on PL, acting as a gut lipid sink to achieve better lipidemia and CVD risk control in T2D.
Berberine
Glucose and metabolic health markers is closer to a research marker, so it should be read separately from a directly felt benefit.
Representative tier calculated from paper evidence that passed the collection audit.
Main benefit evidence
The representative ingredient tier is calculated from these target-level evidence groups.
Glucose and metabolic health4 studiesTier-BGlucose and metabolic health markersFairly consistent positive signal in studiesResearch marker focusPatient-group studyThis card is closer to a measured biomarker or lab outcome than a directly felt user benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Nutrient status2 studiesTier-CNutrient status markersFairly consistent positive signal in studiesResearch marker focusPatient-group studyThis card is closer to a measured biomarker or lab outcome than a directly felt user benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Stress and mood1 studiesTier-CStress Response and Sleep ChangesSome positive signal observedFelt benefit focusPatient-group studyThese findings come from stress response, cortisol, anxiety, or sleep outcomes. They may mix felt benefits with physiological markers.Open metrics>
Blood lipids1 studiesTier-CCholesterol and triglyceridesSignal is still limitedFelt benefit focusPatient-group studyPotential benefit studied in Blood lipids.Open metrics>
Digestion and gut health1 studiesTier-CDigestion and gut comfortSignal is still limitedFelt benefit focusPatient-group studyPotential benefit studied in Digestion and gut health.Open metrics>
Immune and respiratory health2 studiesTier-CImmune and respiratory supportSignal is still limitedFelt benefit focusPatient-group studyPotential benefit studied in Immune and respiratory health.Open metrics>
Recent research
10 new papers were added in this period. No new risk signal was identified.
What's new
Most notable recent finding
Key cautions to review
Standalone side-effect signals and combination cautions are listed separately.
Side-effect and combination signals
No standalone side-effect or combination signal is currently clear enough to show from the collected papers. This does not mean there is no concern.
Evidence summaries
Paper IDs and full lists are private. Only study types and summaries are shown.
A deeper understanding of berberine's effectiveness is delves into by integrating network pharmacology and molecular docking techniques in the context of treating inflammatory diseases, providing guidance and reference for berberine's subsequent revelation of
Animal experiments showed that BBR located favorably in the liver and altered hepatic metabolism-related gene expression in an animal model of NAFLD treated with BBR, suggesting that the therapeutic effect of BBR may involve a direct regulation of hepatic lipi
3 more summariesLimited representative sample by study type.>
It is shown that BBR supplementation reverts mitochondrial dysfunction induced by High Fat Diet and hyperglycemia in skeletal muscle, in part due to an increase in mitochondrial biogenesis, and an important role for SIRT1 and mitochondrialBiogenesis in the pre
It is found that berberine can work as an anti-inflammatory and antioxidant, where the state of inflammation and oxidative stress itself has an influence on the condition of diabetes mellitus.
Taken together, berberine could alleviate intestinal barrier damage injured by high-fat or high-carbohydrate diet and improve the growth performance of blunt snout bream.