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Tier-CPublic-ready6/11/2026

Zinc

Glucose and metabolic health markers is closer to a research marker, so it should be read separately from a directly felt benefit.

Representative tier calculated from paper evidence that passed the collection audit.

Papers analyzed
20
Caution signal
Low
Representative score
47.2
Glucose and metabolic health markersNutrient status markersCondition-specific health context in a specific context

Main benefit evidence

The representative ingredient tier is calculated from these target-level evidence groups.

Glucose and metabolic health
4 studiesTier-B
Glucose and metabolic health markers
Fairly consistent positive signal in studiesResearch marker focusPatient-group study
This card is closer to a measured biomarker or lab outcome than a directly felt user benefit.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Glucose and metabolic markers
No direct rate reported. Read direction and evidence strength together.
Evidence score
54.6
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Nutrient status
4 studiesTier-B
Nutrient status markers
Fairly consistent positive signal in studiesResearch marker focusPatient-group study
This card is closer to a measured biomarker or lab outcome than a directly felt user benefit.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Nutrient status and deficiency markers
No direct rate reported. Read direction and evidence strength together.
Evidence score
54.6
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Condition-specific evidence
2 studiesTier-C
Condition-specific health context in a specific context
Fairly consistent positive signal in studiesResearch marker focusSupplement context
This result was studied for Condition-specific health context in a narrower population or condition-specific context. It should not be generalized as an everyday supplement effect.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Condition-specific health context
No direct rate reported. Read direction and evidence strength together.
Evidence score
48.7
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Stress and mood
1 studiesTier-C
Stress Response and Sleep Changes
Some positive signal observedFelt benefit focusPatient-group study
These findings come from stress response, cortisol, anxiety, or sleep outcomes. They may mix felt benefits with physiological markers.
Open metrics
>
Stress and mood balance
No direct rate reported. Read direction and evidence strength together.
Evidence score
42.1
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Immune and respiratory health
3 studiesTier-C
Immune and respiratory support
Some positive signal observedFelt benefit focusPatient-group study
Potential benefit studied in Immune and respiratory health.
Open metrics
>
Immune and respiratory support
No direct rate reported. Read direction and evidence strength together.
Evidence score
19.7
Score reflects signal strength. Tier also considers paper count, repetition, and study context.

Research clues (read separately)

Disease-specific, biomarker, animal, or cell-study findings — not everyday felt benefits.

Specialized clinical context
1 studiesTier-C
Specialized Treatment-Setting Signal
Some positive signal observedDisease markerSpecialized treatment
This evidence comes from contexts such as cancer, mortality, hospitalization, drug combination, or radiation studies. It should not be read as a general supplement effect.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Immune and respiratory support
No direct rate reported. Read direction and evidence strength together.
Evidence score
35.0
Score reflects signal strength. Tier also considers paper count, repetition, and study context.

Recent research

Updated This Month10 new papers

10 new papers were added in this period. No new risk signal was identified.

What's new

10 new papers were added.No new risk signal was identified.

Most notable recent finding

This is the most meaningful new study in the latest update.
review
Why it mattersIt ranked highest among the newly collected papers for this ingredient in the latest update.
View paper

Study dosage range (reference only)

Lower dose
30
mg/day
Higher dose
30
mg/day
Dosages used in research papers, shown as reference context.
Not personal dosing instructions, recommendations, or safety limits.

Key cautions to review

Standalone side-effect signals and combination cautions are listed separately.

Caution index
0.4
Caution band: Low
Caution signals
0
Side effects + combos + curated rules
Key precautions
No combination caution signal is clear enough to show right now. This does not guarantee safety.
1 combo signals and 0 added-signal combos shown below.
Standalone side effects, combination cautions, and positive combos are separated below.

Combinations studied together

The group showed a positive signal, but individual contributions are hard to isolate. Not a stack recommendation.

+MagnesiumCo-supplementation with magnesium oxide and zinc sulfate resulted in significant improvements in glycemic control, lipid profiles, and inflammatory markers compared to placebo.

Evidence summaries

Paper IDs and full lists are private. Only study types and summaries are shown.

Key Evidence #1
Public scholarly dataCitation signal: 233
observational

It is suggested that treatment with zinc, ascorbic acid, or both does not affect SARS-CoV-2 symptoms, and there was no significant difference in the duration of symptoms among the 4 groups.

Key Evidence #2
Public scholarly dataCitation signal: 140
observational

The notion that zinc supplementation may have clinical potential as an adjunct therapy for preventing or managing diabetes is supported, particularly the FG in subjects with diabetes and in subjects who received an inorganic zinc supplement.

Key Evidence #3
Public scholarly dataCitation signal: 135
observational

Among a general population of couples seeking infertility treatment, the use of folic acid and zinc supplementation by male partners, compared with placebo, did not significantly improve semen quality or couples' live birth rates.

3 more summariesLimited representative sample by study type.
>
Public scholarly dataCitation signal: 121
observational

It is demonstrated that magnesium-zinc-calcium-vitamin D co-supplementation for 6 weeks to women with GDM may reduce biomarkers of inflammation and oxidative stress.

Public scholarly dataCitation signal: 92
review

It is indicated that zinc supplementation in infants and early childhood, but not pregnancy, increases specific growth outcomes, with evidence for a potentially stronger effect after 2 years of age.

Public scholarly dataCitation signal: 82
observational

Providing SQ-LNS daily with or without zinc, along with malaria and diarrhea treatment, significantly increased growth and reduced stunting, wasting and anemia prevalence in young children.

Zinc
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