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arrow_backExplore/Vitamin C
Tier-BPublic-ready6/11/2026

Vitamin C

Immune and respiratory support is the main area connected here, and any felt benefit should be read together with the human evidence base.

Representative tier calculated from paper evidence that passed the collection audit.

Papers analyzed
20
Caution signal
Low
Representative score
66.8
Immune and respiratory supportGlucose and metabolic health markersBlood pressure and vascular health markers

Main benefit evidence

The representative ingredient tier is calculated from these target-level evidence groups.

Immune and respiratory health
2 studiesTier-C
Immune and respiratory support
Fairly consistent positive signal in studiesFelt benefit focusPatient-group study
Potential benefit studied in Immune and respiratory health.
Open metrics
>
Immune and respiratory support
No direct rate reported. Read direction and evidence strength together.
Evidence score
48.7
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Glucose and metabolic health
2 studiesTier-C
Glucose and metabolic health markers
Fairly consistent positive signal in studiesResearch marker focusPatient-group study
This card is closer to a measured biomarker or lab outcome than a directly felt user benefit.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Glucose and metabolic markers
No direct rate reported. Read direction and evidence strength together.
Evidence score
48.7
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Blood pressure and vascular health
2 studiesTier-C
Blood pressure and vascular health markers
Fairly consistent positive signal in studiesResearch marker focusPatient-group study
This card is closer to a measured biomarker or lab outcome than a directly felt user benefit.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Blood pressure and vascular markers
No direct rate reported. Read direction and evidence strength together.
Evidence score
48.7
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Blood lipids
3 studiesTier-C
Cholesterol and triglycerides
Fairly consistent positive signal in studiesFelt benefit focusPatient-group study
Potential benefit studied in Blood lipids.
Open metrics
>
Cholesterol and triglycerides
No direct rate reported. Read direction and evidence strength together.
Evidence score
45.8
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Women's health
1 studiesTier-C
Menstrual and women's health
Some positive signal observedFelt benefit focusPatient-group study
Potential benefit studied in Women's health.
Open metrics
>
Menstrual and women's health
No direct rate reported. Read direction and evidence strength together.
Evidence score
44.0
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Condition-specific evidence
3 studiesTier-C
Condition-specific health context in a specific context
Some positive signal observedResearch marker focusSupplement context
This result was studied for Condition-specific health context in a narrower population or condition-specific context. It should not be generalized as an everyday supplement effect.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Condition-specific health context
No direct rate reported. Read direction and evidence strength together.
Evidence score
42.6
Score reflects signal strength. Tier also considers paper count, repetition, and study context.

Recent research

Updated This Month10 new papers

10 new papers were added in this period. No new risk signal was identified.

What's new

10 new papers were added.No new risk signal was identified.

Most notable recent finding

This is the most meaningful new study in the latest update.
review
Why it mattersIt ranked highest among the newly collected papers for this ingredient in the latest update.
View paper

Study dosage range (reference only)

Lower dose
1000
mg/day
Higher dose
1000
mg/day
Dosages used in research papers, shown as reference context.
Not personal dosing instructions, recommendations, or safety limits.

Key cautions to review

Standalone side-effect signals and combination cautions are listed separately.

Caution index
0.6
Caution band: Low
Caution signals
0
Side effects + combos + curated rules
Key precautions
No combination caution signal is clear enough to show right now. This does not guarantee safety.
Standalone side effects, combination cautions, and positive combos are separated below.

Side-effect and combination signals

No standalone side-effect or combination signal is currently clear enough to show from the collected papers. This does not mean there is no concern.

Evidence summaries

Paper IDs and full lists are private. Only study types and summaries are shown.

Key Evidence #1
Public scholarly dataCitation signal: 190
observational

Supplemental vitamin C to pregnant smokers improved newborn PFTs and decreased wheezing through 1 year in the offspring and may be an inexpensive and simple approach to decrease the effects of smoking in pregnancy on newborn pulmonary function and respiratory

Key Evidence #2
Public scholarly dataCitation signal: 172
observational

Vitamin C (500 mg twice daily) has potential effects in alleviating inflammatory status by reducing hs-CRP, IL-6, and FBG in hypertensive and/or diabetic obese patients.

Key Evidence #3
Public scholarly dataCitation signal: 157
observational

Antioxidants do not improve semen parameters or DNA integrity among men with male factor infertility, and this study suggests that antioxidant treatment of the male partner does not improve in vivo pregnancy or live birth rate.

3 more summariesLimited representative sample by study type.
>
Public scholarly dataCitation signal: 141
meta-analysis

To assess the effect of vitamin C supplementation on serum uric acid (SUA) by pooling the findings from published randomized controlled trials (RCTs), a database of RCTs is constructed.

Public scholarly dataCitation signal: 137
observational

The intake of vitamin C and vitamin E supplements effectively reduced dysmenorrhea severity and improved dyspareunia and severity of pelvic pain, and support the potential role of antioxidants in the management of endometriosis.

Public scholarly dataCitation signal: 102
review

Investigation of the efficacy of oral vitamin C supplementation in improving glycemic control, cardiovascular risk factors, and oxidative stress in people with type 2 diabetes found it cannot currently be recommended as a therapy until larger, long-term, and h

Vitamin C
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