biotech

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Tier-CPublic-ready6/11/2026

Vitamin A

Menstrual and women's health is the main area connected here, and any felt benefit should be read together with the human evidence base.

Representative tier calculated from paper evidence that passed the collection audit.

Papers analyzed
20
Caution signal
Low
Representative score
41.8
Menstrual and women's healthNutrient status markersSpecialized Treatment-Setting Signal

Main benefit evidence

The representative ingredient tier is calculated from these target-level evidence groups.

Women's health
1 studiesTier-C
Menstrual and women's health
Some positive signal observedFelt benefit focusPatient-group study
Potential benefit studied in Women's health.
Open metrics
>
Menstrual and women's health
No direct rate reported. Read direction and evidence strength together.
Evidence score
42.1
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Nutrient status
1 studiesTier-C
Nutrient status markers
Some positive signal observedResearch marker focusSupplement context
This card is closer to a measured biomarker or lab outcome than a directly felt user benefit.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Nutrient status and deficiency markers
No direct rate reported. Read direction and evidence strength together.
Evidence score
40.5
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Specialized clinical context
2 studiesTier-C
Specialized Treatment-Setting Signal
Some positive signal observedDisease markerSupplement context
This evidence comes from contexts such as cancer, mortality, hospitalization, drug combination, or radiation studies. It should not be read as a general supplement effect.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Specialized disease or hospital-context outcomesNutrient status and deficiency markers
No direct rate reported. Read direction and evidence strength together.
Evidence score
37.9
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Condition-specific evidence
2 studiesTier-C
Condition-specific health context in a specific context
Some positive signal observedResearch marker focusSupplement context
This result was studied for Condition-specific health context in a narrower population or condition-specific context. It should not be generalized as an everyday supplement effect.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Condition-specific health context
No direct rate reported. Read direction and evidence strength together.
Evidence score
26.1
Score reflects signal strength. Tier also considers paper count, repetition, and study context.

Recent research

Updated This Month10 new papers

10 new papers were added in this period. No new risk signal was identified.

What's new

10 new papers were added.No new risk signal was identified.

Most notable recent finding

This is the most meaningful new study in the latest update.
review
Why it mattersIt ranked highest among the newly collected papers for this ingredient in the latest update.
View paper

Key cautions to review

Standalone side-effect signals and combination cautions are listed separately.

Caution index
1.1
Caution band: Low
Caution signals
0
Side effects + combos + curated rules
Key precautions
No combination caution signal is clear enough to show right now. This does not guarantee safety.
Standalone side effects, combination cautions, and positive combos are separated below.

Side-effect and combination signals

No standalone side-effect or combination signal is currently clear enough to show from the collected papers. This does not mean there is no concern.

Evidence summaries

Paper IDs and full lists are private. Only study types and summaries are shown.

Key Evidence #1
Public scholarly dataCitation signal: 506
observational

New evidence for both prevalence and absolute burden of vitamin A deficiency should be used to reconsider, and possibly revise, the list of priority countries for high-dose vitamin A supplementation such that a country's priority status takes into account both

Key Evidence #2
Public scholarly dataCitation signal: 210
review

This work examined data from 82 countries implementing VAS programs, identified other VA programs, and assessed the recentness of national VA deficiency (VAD) data, and identified three countries that have scaled down VAS, but given the lack of VA deficiency d

Key Evidence #3
Public scholarly dataCitation signal: 198
observational

β-Carotene from maize was efficacious when consumed as a staple food in this population and could avoid the potential for hypervitaminosis A that was observed with the use of preformed VA from supplementation and fortification.

3 more summariesLimited representative sample by study type.
>
Public scholarly dataCitation signal: 190
meta-analysis

Beta-carotene and vitamin E in doses higher than the RDA seem to significantly increase mortality, whereas the authors lack information on vitamin A.

Public scholarly dataCitation signal: 184
review

An extensive review of the literature was conducted to identify conflicting or incomplete data on the topic as well as any gaps in existing data, and recommend routine prenatal vitamin A supplementation for the prevention of maternal and infant morbidity and m

Public scholarly dataCitation signal: 158
review

A systematic review of published randomized controlled trials (RCTs) and quasi-experimental (QE) studies found that vaccination was effective in preventing measles disease and vitamin A treatment found no significant reduction in measles morality.

Vitamin A
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