Stress Response and Sleep Changes is the main area connected here, and any felt benefit should be read together with the human evidence base.
Some human supplement-context evidence is present and directly informs the score.
Representative tier calculated from paper evidence that passed the collection audit.
The representative ingredient tier is calculated from these target-level evidence groups.
10 new papers were added in this period. No new risk signal was identified.
Standalone side-effect signals and combination cautions are listed separately.
Paper IDs and full lists are private. Only study types and summaries are shown.
The selective interactions of valerian extract and valerenic acid with Group I and Group II mGluR may represent an alternative explanation for the anxiolytic properties of this plant.
Valerian could be a safe and effective herb to promote sleep and prevent associated disorders, however, due to the presence of multiple active constituents and relatively unstable nature of some of the active constituents, it may be necessary to revise the qua
Valerian appears to be safe, but with modest beneficial effects at most on insomnia compared to placebo, and the combined use of television and the Internet in randomised trials offers opportunities to answer questions about the effects of health care interven
Valerenic acid and valerian extracts have anticonvulsant properties in adult zebrafish and markedly enhanced the anticonVulsant effect of both clonazepam and phenytoin, and could contribute to therapy of epileptic patients.
Olfactory enrichment for cats may have great potential, and silver vine and Tatarian honeysuckle appear to be good alternatives to catnip for domestic cats that do not respond toCatnip.
Valerian significantly improved sleep quality, the symptoms of state anxiety, and depression in HD patients.