It is found that the dietary fibers or probiotics may relieve hard stool, with intervention-specific changes in gut microbiota relevant to constipation relief, in 250 adults with functional constipation.
Psyllium
Glucose and metabolic health markers is closer to a research marker, so it should be read separately from a directly felt benefit.
Representative tier calculated from paper evidence that passed the collection audit.
Main benefit evidence
The representative ingredient tier is calculated from these target-level evidence groups.
Glucose and metabolic health9 studiesTier-BGlucose and metabolic health markersFairly consistent positive signal in studiesResearch marker focusPatient-group studyThis card is closer to a measured biomarker or lab outcome than a directly felt user benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Blood lipids5 studiesTier-BCholesterol and triglyceridesFairly consistent positive signal in studiesFelt benefit focusPatient-group studyPotential benefit studied in Blood lipids.Open metrics>
Digestion and gut health4 studiesTier-BDigestion and gut comfortFairly consistent positive signal in studiesFelt benefit focusPatient-group studyPotential benefit studied in Digestion and gut health.Open metrics>
Condition-specific evidence2 studiesTier-CCondition-specific health context in a specific contextFairly consistent positive signal in studiesResearch marker focusSupplement contextThis result was studied for Condition-specific health context in a narrower population or condition-specific context. It should not be generalized as an everyday supplement effect.Closer to a research marker than a directly felt benefit.Open metrics>
Blood pressure and vascular health2 studiesTier-CBlood pressure and vascular health markersFairly consistent positive signal in studiesResearch marker focusPatient-group studyThis card is closer to a measured biomarker or lab outcome than a directly felt user benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Immune and respiratory health1 studiesTier-CImmune and respiratory supportSome positive signal observedFelt benefit focusPatient-group studyPotential benefit studied in Immune and respiratory health.Open metrics>
Recent research
10 new papers were added in this period. No new risk signal was identified.
What's new
Most notable recent finding
Key cautions to review
Standalone side-effect signals and combination cautions are listed separately.
Side-effect and combination signals
No standalone side-effect or combination signal is currently clear enough to show from the collected papers. This does not mean there is no concern.
Evidence summaries
Paper IDs and full lists are private. Only study types and summaries are shown.
Patients with FI may experience a reduction in FI frequency after psyllium supplementation, and decreased FI frequency has been shown to be an important personal goal of treatment for patients with FI.
The reduction in glycemic response was enhanced by combining soluble fiber to the normal diet and consumption of foods containing moderate amounts of these fibers may improve glucose metabolism and lipid profile in type 2 diabetes patients.
3 more summariesLimited representative sample by study type.>
Children in the psyllium group had a greater reduction in the mean number of pain episodes than children in the placebo group, independent of psychological factors.
In patients with T2D and chronic constipation, psyllium supplementation decreased constipation symptoms, body weight, glycemic, cholesterol, and increased HDLC levels.
Psyllium fiber supplementation did not significantly reduce CRP levels in overweight or obese individuals in this trial, and changes in other markers were not consistent.