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arrow_backExplore/Pantothenic Acid
Tier-CPublic-ready6/11/2026

Pantothenic Acid

Condition-specific health context in a specific context is closer to a research marker, so it should be read separately from a directly felt benefit.

Representative tier calculated from paper evidence that passed the collection audit.

Papers analyzed
20
Caution signal
Low
Representative score
19.9
Condition-specific health context in a specific contextStress Response and Sleep ChangesNutrient status markers

Main benefit evidence

The representative ingredient tier is calculated from these target-level evidence groups.

Condition-specific evidence
3 studiesTier-B
Condition-specific health context in a specific context
Fairly consistent positive signal in studiesResearch marker focusSupplement context
This result was studied for Condition-specific health context in a narrower population or condition-specific context. It should not be generalized as an everyday supplement effect.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Condition-specific health context
No direct rate reported. Read direction and evidence strength together.
Evidence score
52.0
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Stress and mood
1 studiesTier-C
Stress Response and Sleep Changes
Some positive signal observedFelt benefit focusSupplement context
These findings come from stress response, cortisol, anxiety, or sleep outcomes. They may mix felt benefits with physiological markers.
Open metrics
>
Stress and mood balance
No direct rate reported. Read direction and evidence strength together.
Evidence score
25.3
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Nutrient status
1 studiesTier-C
Nutrient status markers
Some positive signal observedResearch marker focusSupplement context
This card is closer to a measured biomarker or lab outcome than a directly felt user benefit.
Closer to a research marker than a directly felt benefit.
Open metrics
>
Nutrient status and deficiency markers
No direct rate reported. Read direction and evidence strength together.
Evidence score
20.9
Score reflects signal strength. Tier also considers paper count, repetition, and study context.

Recent research

Updated This Month10 new papers

10 new papers were added in this period. No new risk signal was identified.

What's new

10 new papers were added.No new risk signal was identified.

Most notable recent finding

This is the most meaningful new study in the latest update.
review
Why it mattersIt ranked highest among the newly collected papers for this ingredient in the latest update.
View paper

Key cautions to review

Standalone side-effect signals and combination cautions are listed separately.

Caution index
0.5
Caution band: Low
Caution signals
1
Side effects + combos + curated rules
Key precautions
No combination caution signal is clear enough to show right now. This does not guarantee safety.
Standalone side effects, combination cautions, and positive combos are separated below.

Standalone side effects

intestinal function and energy metabolism1 papers
Pantothenic acid deficiency in ducks leads to growth depression, intestinal hypofunction, impaired energy generation, and abnormal intestinal absorption.animal · animal-study

Evidence summaries

Paper IDs and full lists are private. Only study types and summaries are shown.

Key Evidence #1
Public scholarly dataCitation signal: 350
review

The present review aims to outline the current understanding of the mechanisms involved in intestinal absorption of water-soluble vitamins, their regulation, the cell biology of the carriers involved and the factors that negatively affect these absorptive even

Key Evidence #2
Public scholarly dataCitation signal: 90
observational

It is found that widespread, severe cerebral deficiency of vitamin B5 occurs in AD, and this deficiency was worse in those regions known to undergo severe damage, including the hippocampus, entorhinal cortex, and middle temporal gyrus.

Key Evidence #3
Public scholarly dataCitation signal: 59
observational

A higher intake of dietary B vitamins, especially biotin, was associated with a lower prevalence of depression, anxiety, and stress symptoms, and the role of B vitamins requires further investigation in randomized controlled trials.

3 more summariesLimited representative sample by study type.
>
Public scholarly dataCitation signal: 55
observational

This is the first reporting of mutations in the SLC5A6 gene in man, and suggests that this gene is important for brain development and a wide variety of clinical functions.

Public scholarly dataCitation signal: 39
observational

The addition of pantothenic acid in the diet of one-to four-week-old Wulong geese significantly affected the growth performance, slaughter performance, lipid metabolism, cholesterol metabolism, and antioxidant function of the geese.

Public scholarly dataCitation signal: 32
observational

Observations indicate a common but regionally selective disruption of pantothenic acid levels across PDD, ADD, and HD.

Pantothenic Acid
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