Focus group discussions revealed how previous and anticipated negative interactions with physicians and skepticism about the healthcare system have alienated young Black MSM from the health care system and created significant barriers to PrEP.
MSM
Bone, joint, and mobility is the main area connected here, and any felt benefit should be read together with the human evidence base.
Representative tier calculated from paper evidence that passed the collection audit.
Main benefit evidence
The representative ingredient tier is calculated from these target-level evidence groups.
Bone and joint health3 studiesTier-BBone, joint, and mobilityFairly consistent positive signal in studiesFelt benefit focusPatient-group studyPotential benefit studied in Bone and joint health.Open metrics>
Condition-specific evidence1 studiesTier-CCondition-specific health context in a specific contextSome positive signal observedResearch marker focusSupplement contextThis result was studied for Condition-specific health context in a narrower population or condition-specific context. It should not be generalized as an everyday supplement effect.Closer to a research marker than a directly felt benefit.Open metrics>
Immune and respiratory health1 studiesTier-CImmune and respiratory supportSome positive signal observedFelt benefit focusSupplement contextPotential benefit studied in Immune and respiratory health.Open metrics>
Stress and mood1 studiesTier-CStress Response and Sleep ChangesSome positive signal observedFelt benefit focusSupplement contextThese findings come from stress response, cortisol, anxiety, or sleep outcomes. They may mix felt benefits with physiological markers.Open metrics>
Nutrient status1 studiesTier-CNutrient status markersSome positive signal observedResearch marker focusPatient-group studyThis card is closer to a measured biomarker or lab outcome than a directly felt user benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Exercise performance and recovery1 studiesTier-CExercise performance and recoverySignal is still limitedFelt benefit focusSupplement contextPotential benefit studied in Exercise performance and recovery.Open metrics>
Recent research
10 new papers were added in this period. No new risk signal was identified.
What's new
Most notable recent finding
Key cautions to review
Standalone side-effect signals and combination cautions are listed separately.
Standalone side effects
Evidence summaries
Paper IDs and full lists are private. Only study types and summaries are shown.
Results depict an HA outbreak of multiple HAV strains, within a cross-European population, that was particularly driven by transmission between non-immune MSM engaging in high-risk sexual behaviour.
As a Generally Recognized As Safe (GRAS) approved substance, MSM is well-tolerated by most individuals at dosages of up to four grams daily, with few known and mild side effects.
3 more summariesLimited representative sample by study type.>
There was no evidence of risk compensation among HIV-uninfected MSM in this clinical trial and monitoring for risk compensation should continue now that preexposure prophylaxis has been shown to be efficacious in MSM and other populations.
While some MSM engaging in chemsex and SDU appeared content with these behaviours, the association with life satisfaction and sexual self-efficacy indicates psychosocial support is needed for some, and the importance of promoting harm reduction among this popu
Among MSM on PrEP, there were decreases in condom use, and a higher prevalence of STIs during PrEP use compared to prior to PrEP initiation, and there was no change in number of sexual partners or reporting HIV-positive or HIV-negative partners.