L-carnitine supplementation provides a modest reducing effect on body weight, BMI and fat mass, especially among adults with overweight/obesity, and suggests that ingestion of 2000 mg l-c Carnitine per day provides the maximum effect in adults.
L-Carnitine
Exercise performance and recovery is the main area connected here, and any felt benefit should be read together with the human evidence base.
Representative tier calculated from paper evidence that passed the collection audit.
Main benefit evidence
The representative ingredient tier is calculated from these target-level evidence groups.
Exercise performance and recovery4 studiesTier-BExercise performance and recoveryFairly consistent positive signal in studiesFelt benefit focusSupplement contextPotential benefit studied in Exercise performance and recovery.Open metrics>
Nutrient status4 studiesTier-BNutrient status markersFairly consistent positive signal in studiesResearch marker focusPatient-group studyThis card is closer to a measured biomarker or lab outcome than a directly felt user benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Blood lipids4 studiesTier-BCholesterol and triglyceridesFairly consistent positive signal in studiesFelt benefit focusPatient-group studyPotential benefit studied in Blood lipids.Open metrics>
Immune and respiratory health1 studiesTier-CImmune and respiratory supportSome positive signal observedFelt benefit focusPatient-group studyPotential benefit studied in Immune and respiratory health.Open metrics>
Stress and mood1 studiesTier-CStress Response and Sleep ChangesSome positive signal observedFelt benefit focusPatient-group studyThese findings come from stress response, cortisol, anxiety, or sleep outcomes. They may mix felt benefits with physiological markers.Open metrics>
Men's health1 studiesTier-CMale Reproductive Health MarkersSome positive signal observedResearch marker focusSupplement contextThese findings come from sperm, semen, or hormone markers such as testosterone, LH, FSH, and inhibin B. They are closer to research measurements than a directly felt benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Recent research
10 new papers were added in this period. No new risk signal was identified.
What's new
Most notable recent finding
Study dosage range (reference only)
Key cautions to review
Standalone side-effect signals and combination cautions are listed separately.
Combinations studied together
The group showed a positive signal, but individual contributions are hard to isolate. Not a stack recommendation.
Evidence summaries
Paper IDs and full lists are private. Only study types and summaries are shown.
It is demonstrated that l-carnitine alleviates muscle injury and reduces markers of cellular damage and free radical formation accompanied by attenuation of muscle soreness, thereby reducing hypoxia-induced cellular and biochemical disruptions.
LC supplementation at a dose of 1000 mg/d was associated with a significant reduction in oxidative stress and an increase in antioxidant enzymes activities in CAD patients, which might benefit from using LC supplements to increase their anti-oxidation capacity
3 more summariesLimited representative sample by study type.>
Prolonged LC supplementation in specific conditions may affect physical performance and LC supplementation elevates fasting plasma TMAO, compound supposed to be pro-atherogenic, which was not associated with modification of determined inflammatory nor oxidativ
This double-blind parallel study provides evidences supporting the beneficial effects of Coenzyme Q10 and L-carnitine supplements on serum levels of lactate and migraine symptoms.
[Abstract]: The wide use of high-fat diet (HFD) causes negative effects on flesh quality in farmed fish. l-carnitine, a lipid-lowering additive, enhances mitochondrial fatty acid β-oxidation. However its roles in alleviating the effects of HFD on flesh quality