[Abstract]: OBJECTIVE To check the hypothesis that myo-inositol supplementation may reduce gestational diabetes mellitus (GDM) onset in pregnant women with a family history of type 2 diabetes. RESEARCH DESIGN AND METHODS A 2-year, prospective, randomized, open
Inositol
Glucose and metabolic health markers is closer to a research marker, so it should be read separately from a directly felt benefit.
Representative tier calculated from paper evidence that passed the collection audit.
Main benefit evidence
The representative ingredient tier is calculated from these target-level evidence groups.
Glucose and metabolic health6 studiesTier-BGlucose and metabolic health markersFairly consistent positive signal in studiesResearch marker focusPatient-group studyThis card is closer to a measured biomarker or lab outcome than a directly felt user benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Women's health4 studiesTier-BMenstrual and women's healthFairly consistent positive signal in studiesFelt benefit focusPatient-group studyPotential benefit studied in Women's health.Open metrics>
Blood lipids2 studiesTier-CCholesterol and triglyceridesFairly consistent positive signal in studiesFelt benefit focusPatient-group studyPotential benefit studied in Blood lipids.Open metrics>
Recent research
10 new papers were added in this period. No new risk signal was identified.
What's new
Most notable recent finding
Key cautions to review
Standalone side-effect signals and combination cautions are listed separately.
Side-effect and combination signals
No standalone side-effect or combination signal is currently clear enough to show from the collected papers. This does not mean there is no concern.
Evidence summaries
Paper IDs and full lists are private. Only study types and summaries are shown.
The trial sequential analysis of insulin meta-analysis illustrates that the cumulative z-curve crossed the monitoring boundary, providing firm evidence of the intervention effect of MI in improving the metabolic profile of women with PCOS, concomitantly reduci
In women with PCOS, increased glucose-stimulated DCI-IPG release is significantly correlated with improved insulin sensitivity, and the significant relationship between DCI-IPG release and insulin sensitivity suggests that the DCI-IPG mediator may be a target
3 more summariesLimited representative sample by study type.>
[Abstract]: OBJECTIVE Better preconception metabolic and nutritional health are hypothesized to promote gestational normoglycemia and reduce preterm birth, but evidence supporting improved outcomes with nutritional supplementation starting preconception is lim
Overall, taking myo-inositol, compared with metformin, for 12 weeks by women with PCOS had beneficial effects on glycemic control, triglycerides and VLDL-cholesterol levels, and gene expression of PPAR-γ.
Inositol supplementation may result in reduction in triglycerides, total- and LDL-cholesterol levels, but did not affect HDL-ch cholesterol levels among patients with metabolic diseases.