Key Evidence #1
observationalPublic scholarly dataCitation signal: 148
The validation of a human enzyme that methylates the ribose of the second transcribed nucleotide encoded by FTSJD1 is reported, henceforth renamed HMTR2 to reflect function.
Tier-CPublic-ready6/13/2026
D-Ribose
Exercise performance and recovery is the main area connected here, and any felt benefit should be read together with the human evidence base.
Representative tier calculated from paper evidence that passed the collection audit.
Papers analyzed
20
Caution signal
Low
Representative score
0.0
Exercise performance and recoveryBlood pressure and vascular health markers
Main benefit evidence
The representative ingredient tier is calculated from these target-level evidence groups.
Exercise performance and recovery1 studiesTier-CExercise performance and recoverySome positive signal observedFelt benefit focusSupplement contextPotential benefit studied in Exercise performance and recovery.Open metrics>
Exercise performance and recovery
1 studiesTier-C
Exercise performance and recovery
Some positive signal observedFelt benefit focusSupplement context
Potential benefit studied in Exercise performance and recovery.
Open metrics
>Exercise performance and recovery
No direct rate reported. Read direction and evidence strength together.
Evidence score
44.0
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Blood pressure and vascular health1 studiesTier-CBlood pressure and vascular health markersSignal is still limitedResearch marker focusPatient-group studyThis card is closer to a measured biomarker or lab outcome than a directly felt user benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Blood pressure and vascular health
1 studiesTier-C
Blood pressure and vascular health markers
Signal is still limitedResearch marker focusPatient-group study
This card is closer to a measured biomarker or lab outcome than a directly felt user benefit.
Closer to a research marker than a directly felt benefit.
Open metrics
>Blood pressure and vascular markers
No direct rate reported. Read direction and evidence strength together.
Evidence score
11.7
Score reflects signal strength. Tier also considers paper count, repetition, and study context.
Recent research
Updated This Month10 new papers
10 new papers were added in this period. No new risk signal was identified.
What's new
10 new papers were added.No new risk signal was identified.
Most notable recent finding
This is the most meaningful new study in the latest update.
Why it mattersIt ranked highest among the newly collected papers for this ingredient in the latest update.
View paperStudy dosage range (reference only)
Lower dose
1520
mg/dayHigher dose
1520
mg/dayDosages used in research papers, shown as reference context.
Not personal dosing instructions, recommendations, or safety limits.
Key cautions to review
Standalone side-effect signals and combination cautions are listed separately.
Caution index
0.0
Caution band: Low
Caution signals
1
Side effects + combos + curated rules
Key precautions
No combination caution signal is clear enough to show right now. This does not guarantee safety.
Standalone side effects, combination cautions, and positive combos are separated below.
Standalone side effects
Cytotoxicity via glycation and pentose phosphate pathway1 papers
The review highlights that D-ribose administration may cause cytotoxic effects through glycation and forcing ribose-5-phosphate into the pentose phosphate pathway, indicating potential risks.human · unknownEvidence summaries
Paper IDs and full lists are private. Only study types and summaries are shown.
Key Evidence #2
observationalPublic scholarly dataCitation signal: 70
Growth of Bifidobacterium breve UCC2003 on ribose leads to the transcriptional induction of the rbsACBDK gene cluster, which is essential for ribose utilization and its transcription is likely regulated by a LacI‐type regulator encoded by rbsR, located immedia
Key Evidence #3
observationalPublic scholarly dataCitation signal: 69
This study provides the first direct experimental evidence for the essentiality of DprE1 in mycobacteria, and validates DprE1 as a promising target for new anti-mycobacterial drugs.
3 more summariesLimited representative sample by study type.>
Public scholarly dataCitation signal: 49
observationalIn this article, it is reviewed how energy is produced by cellular respiration, the pentose pathway, and the use of supplemental D-ribose, a naturally occurring monosaccharide found in the cells and particularly in the mitochondria.
Public scholarly dataCitation signal: 44
observationalThe results suggest that in vitro glycation of bone using glucose leads to the formation of lower levels of AGEs including PEN, whereas ribosylation appears to support a pathway toward PEN formation.
Public scholarly dataCitation signal: 41
observationalIt is suggested that ZAP-mediated viral mRNA degradation is facilitated by PAR, and provides a biophysical rationale for the reported association of ZAP with RNA stress granules.
D-Ribose
arrow_backBack to listEvidence score: 0.0|Caution index: 0.0