CoQ10 supplementation does not reduce muscle pain in patients with statin myalgia and only 36% of patients complaining of statin myalgia develop symptoms during a randomized, double-blind crossover of statin vs placebo.
Coenzyme Q10
Cholesterol and triglycerides is the main area connected here, and any felt benefit should be read together with the human evidence base.
Representative tier calculated from paper evidence that passed the collection audit.
Main benefit evidence
The representative ingredient tier is calculated from these target-level evidence groups.
Blood lipids3 studiesTier-BCholesterol and triglyceridesFairly consistent positive signal in studiesFelt benefit focusPatient-group studyPotential benefit studied in Blood lipids.Open metrics>
Glucose and metabolic health2 studiesTier-CGlucose and metabolic health markersFairly consistent positive signal in studiesResearch marker focusPatient-group studyThis card is closer to a measured biomarker or lab outcome than a directly felt user benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Immune and respiratory health1 studiesTier-CImmune and respiratory supportSome positive signal observedFelt benefit focusPatient-group studyPotential benefit studied in Immune and respiratory health.Open metrics>
Blood pressure and vascular health1 studiesTier-CBlood pressure and vascular health markersSome positive signal observedResearch marker focusPatient-group studyThis card is closer to a measured biomarker or lab outcome than a directly felt user benefit.Closer to a research marker than a directly felt benefit.Open metrics>
Condition-specific evidence1 studiesTier-CCondition-specific health context in a specific contextSome positive signal observedResearch marker focusSupplement contextThis result was studied for Condition-specific health context in a narrower population or condition-specific context. It should not be generalized as an everyday supplement effect.Closer to a research marker than a directly felt benefit.Open metrics>
Fatigue and energy1 studiesTier-CFatigue and energySome positive signal observedFelt benefit focusPatient-group studyPotential benefit studied in Fatigue and energy.Open metrics>
Recent research
10 new papers were added in this period. No new risk signal was identified.
What's new
Most notable recent finding
Key cautions to review
Standalone side-effect signals and combination cautions are listed separately.
Combinations studied together
The group showed a positive signal, but individual contributions are hard to isolate. Not a stack recommendation.
Evidence summaries
Paper IDs and full lists are private. Only study types and summaries are shown.
Significantly reduced cardiovascular mortality could be seen in those on selenium and coenzyme Q10 intervention and the protective action was not confined to the intervention period, but persisted during the follow-up period.
A 12-year follow-up of a group of healthy elderly participants that were supplemented with selenium and coenzyme Q10 for four years validated the results obtained in the 10-year evaluation and observed a significantly reduced risk for CV mortality in this grou
3 more summariesLimited representative sample by study type.>
This double-blind parallel study provides evidences supporting the beneficial effects of Coenzyme Q10 and L-carnitine supplements on serum levels of lactate and migraine symptoms.
CRP and sP-selectin showed significant changes reflecting effects on inflammation and atherosclerosis in those given selenium and coenzyme Q10 combined, and a reduced cardiovascular mortality could be demonstrated in the active group, irrespective of biomarker
The results suggest that CoQ10 plus NADH supplementation for 8 weeks is safe and potentially effective in reducing max HR during a cycle ergometer test and also on fatigue in CFS.