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Public-ready7/4/2026

Citrulline

Papers analyzed
76
Exercise performance and recoveryBlood pressure and vascular health markersGlucose and metabolic health markers
What to look for in this research

Exercise performance and recovery is the main area connected here, and any felt benefit should be read together with the human evidence base.

Main benefit evidence

Review human evidence by goal.

Exercise performance and recovery
Exercise performance and recovery
Measured outcomes: Exercise performance and recovery

Potential benefit studied in Exercise performance and recovery.

Goal tierC
Direct human evidence
Some accumulation3 direct studies
Positive
1
No clear difference
2
Mixed
0
Negative
0
Positive study ratio33%
The share of automatically classified direct studies with a positive result. It is not a personal probability or a certainty assessment.
Research intake observed
One study used 2.4 g/day.
Dose confirmed in 1 of 3 direct studies.
View study intake details
2.4 g/day
rct
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Blood pressure and vascular health
Blood pressure and vascular health markers
Measured outcomes: Blood pressure and vascular markers

This card is closer to a measured biomarker or lab outcome than a directly felt user benefit. These findings come from a defined study population, so everyday effects may differ.

Goal tierNot rated yet

Direct evidence for general supplement use is currently limited under this standard.

2 human studies in a specific clinical context are available separately.

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Glucose and metabolic health
Glucose and metabolic health markers
Measured outcomes: Glucose and metabolic markers

This card is closer to a measured biomarker or lab outcome than a directly felt user benefit. These findings come from a defined study population, so everyday effects may differ.

Goal tierNot rated yet

Direct evidence for general supplement use is currently limited under this standard.

1 human studies in a specific clinical context are available separately.

Check this goal in more detail
Fatigue and energy
Fatigue and energy
Measured outcomes: Fatigue and energy

Potential benefit studied in Fatigue and energy.

Goal tierNot rated yet

The currently linked research coverage is not broad enough to characterize this goal yet.

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What does a research result actually tell you?

Reading research

Side effects and combination findings in studies

Findings from studies of this ingredient alone are separated from findings involving another supplement or medication.

Caution signals
1
Side effects + combos + curated rules
Key precautions
No curated contraindication rule is available yet, but literature caution signals are shown below.
These are signals reported in studies. They do not predict what will happen to an individual.

Findings to review with care

Side effects reported for the ingredient alone are separated from findings involving another supplement or medication.

Side effects reported when this ingredient was used alone

Symptoms or adverse events reported in studies of this ingredient without another active ingredient.

Stomach discomfort1 papers
Stomach discomfort was reported as a side effect in 14.63% of subjects following a single 8g dose of citrulline malate.Human studies · Randomized controlled trial
Citrulline
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