biotech

Bio-Analyst

Research Platform
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Tier-CPublic-ready7/3/2026

Calcium

Menstrual and women's health is the main area connected here, and any felt benefit should be read together with the human evidence base.

The 56.5 score includes research signals from patient or disease contexts. General supplement evidence is not repeated enough, so the C tier remains conservative.

Representative tier calculated from paper evidence that passed the collection audit.

Papers analyzed
52
Caution signal
Low
Context-specific research signal
56.5
Menstrual and women's healthBlood pressure and vascular health markersCholesterol and triglycerides

Main benefit evidence

The representative ingredient tier is calculated from these target-level evidence groups.

Women's health
5 studiesTier-B
Menstrual and women's health
Fairly consistent positive signal in studiesFelt benefit focusPatient-group study

Potential benefit studied in Women's health. These findings come from a defined study population, so everyday effects may differ.

Evidence score
56.7
Study context
Patient-group study

This score reflects the strength of this benefit group. The ingredient tier also considers paper count, repetition, population, and study context.

Blood pressure and vascular health
2 studiesTier-C
Blood pressure and vascular health markers
Fairly consistent positive signal in studiesResearch marker focusPatient-group study

This card is closer to a measured biomarker or lab outcome than a directly felt user benefit. These findings come from a defined study population, so everyday effects may differ.

Evidence score
48.7
Study context
Patient-group study

This score reflects the strength of this benefit group. The ingredient tier also considers paper count, repetition, population, and study context.

Blood lipids
1 studiesTier-C
Cholesterol and triglycerides
Some positive signal observedFelt benefit focusPatient-group study

Potential benefit studied in Blood lipids. These findings come from a defined study population, so everyday effects may differ.

Evidence score
20.9
Study context
Patient-group study

This score reflects the strength of this benefit group. The ingredient tier also considers paper count, repetition, population, and study context.

Glucose and metabolic health
3 studiesTier-C
Glucose and metabolic health markers
Some positive signal observedResearch marker focusPatient-group study

This card is closer to a measured biomarker or lab outcome than a directly felt user benefit. These findings come from a defined study population, so everyday effects may differ.

Evidence score
20.6
Study context
Patient-group study

This score reflects the strength of this benefit group. The ingredient tier also considers paper count, repetition, population, and study context.

Recent research

Updated This Month10 new papers

Observed range in repeated studies

This range includes studies in specific patient groups. It is not a general dose or recommendation.

Lower observed study value
400
mg/day
Higher observed study value
2000
mg/day
Only ranges repeated in human, oral, single-ingredient studies are shown.
Not personal dosing instructions, recommendations, or safety limits.

Side effects and combination findings in studies

Findings from studies of this ingredient alone are separated from findings involving another supplement or medication.

Caution index
1.3
Caution band: Low
Caution signals
4
Side effects + combos + curated rules
Key precautions
No curated contraindication rule is available yet, but literature caution signals are shown below.
These are signals reported in studies. They do not predict what will happen to an individual.

Findings to review with care

Side effects reported for the ingredient alone are separated from findings involving another supplement or medication.

Side effects reported when this ingredient was used alone

Symptoms or adverse events reported in studies of this ingredient without another active ingredient.

Myocardial infarction1 papers
The text reports that studies have refuted myocardial infarction as a side effect of calcium supplementation in older people.Human studies · Study type not identified
Renal stones1 papers
The abstract states that studies have refuted the formation of renal stones as a side effect of calcium supplementation.Human studies · Study type not identified
Abdominal Discomfort1 papers
One patient developed abdominal discomfort attributed to calcium supplementation, leading to a drop-out.Human studies · Observational study

Caution signals when used with another supplement or medication

These studies reported a negative change, reduced absorption, or another caution when substances were used together. They do not predict an individual outcome.

당뇨병Calcium supplementation showed significant multiplicative and additive interaction with diabetes status, increasing CVD risk in diabetic individuals.

Evidence summaries

Paper IDs and full lists are private. Only study types and summaries are shown.

Key Evidence #1
Public scholarly dataCitation signal: 988
review

[Abstract]: Calcium supplementation may prevent high blood pressure through a number of mechanisms and may help to prevent preterm labour. The objective of this review was to assess the effects of calcium supplementation during pregnancy on hypertensive disord

Key Evidence #2
Public scholarly dataCitation signal: 709
review

[Abstract]: This brief review focuses on calcium balance and homeostasis and their relationship to dietary calcium intake and calcium supplementation in healthy subjects and patients with chronic kidney disease and mineral bone disorders (CKD-MBD). Calcium bal

Key Evidence #3
Public scholarly dataCitation signal: 548
review

[Abstract]: Vitamin D and calcium may affect the cardiovascular system independently and interactively. To assess whether vitamin D and calcium supplements reduce the risk for cardiovascular events in adults. Studies published in English from 1966 to July 2009

3 more summariesLimited representative sample by study type.
>
Public scholarly dataCitation signal: 361
review

[Abstract]: Objective To determine whether increasing calcium intake from dietary sources affects bone mineral density (BMD) and, if so, whether the effects are similar to those of calcium supplements. Design Random effects meta-analysis of randomised controll

Public scholarly dataCitation signal: 333
rct

[Abstract]: The purpose of this trial was to determine whether calcium supplementation of pregnant women with low calcium intake reduces preeclampsia and preterm delivery. Randomized placebo-controlled, double-blinded trial in nulliparous normotensive women fr

Public scholarly dataCitation signal: 326
review

[Abstract]: There are striking inequities in calcium intake between rich and poor populations. Appropriate calcium intake has shown many health benefits, such as reduction of hypertensive disorders of pregnancy, lower blood pressure particularly among young pe

Calcium
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